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Proteomics-Based Study of Potential Emphysema Biomarkers Reveals Systemic Redox…

Salai(G),Novak(R),Hrkač(S),Pustka(V),Potěšil… Diagnostics (Basel) 2026-03-21

...ME1) being the only DEP in the CE vs. CN contrast. Proteins such as BMP1, ADAMTSL-2, -4 and IGFBP4, -5, 6 were identifie...

Targeting ME1 rescues redox-metabolic coordination in ALS: A core effector of N…

Yang(Y),Yang(Y),Zhang(X),Ma(H),Ji(S),Zou(F),… Neuropharmacology 2026-08-01

...ME1). Loss-of-function experiments confirmed that ME1 knockdown abolished the protective effects, indicating that the NR...

Functional Characteristics and Stress Tolerance of Microbiota in Botswana's Tra…

Semumu(T),Zhou(N),Lebani(K),Ndlovu(T),Wale(K… Curr Microbiol 2026-04-17

...ME1-B1), B. cereus (GT1-B1) and B. zhangzhouensis were able to withstand baking associated stresses better than all othe...

Antimicrobial and antioxidant activities of Tetracera macrophylla Hook.f. & Tho…

Ahmed(QU),Ab Rahim(MAH),Arzmi(MH),Uddin(AH),… Nat Prod Res 2026-04-11

...ME1, ME2]), among which ME2 exhibited the strongest bioactivity. ME2 showed high total phenolic content (TPC: 254.96 ± 0...

In Vitro Cytotoxic Activity of Coleus hadiensis Methanolic Extract: Metabolic a…

Valdez-Arellanes(AL),Ramírez-Cabrera(MA),Arr… Molecules 2026-03-25

...ME1 correlated with the observed increase in pyruvate levels, while the downregulation of ALDH7A1 and ASRGL1 was linked ...

The Effects of Substituting BHT with a Microencapsulated Basil (Ocimum campechi…

Borges do Vale(R),Coelho Barros(A),Maciel(IJ… Foods 2026-04-03

...ME1 and ME2, respectively). The extracts were analyzed for their antimicrobial activity, antioxidant capacity, and pheno...

Unraveling cellular longevity pathways in poultry under heat stress: functional…

Shamana(K),Edwin(R),Jaishree(SP),Prashanth(D… In Silico Pharmacol None

...ME1, FADS2, ALDH1L2, and DHCR7 showed significant enhancement post-treatment. There was also a restoration of several do...

Malic enzyme 1 contributes to tumorigenesis and lenvatinib resistance in hepato…

Wu(D),Xu(H),Guo(Y),Lu(L),Han(D),Chen(L),Lei(… Cell Death Dis 2026-03-25

...ME1 promoted HCC cell viability in vitro. Consistently, hepatocyte-specific Me1 knockout (Me1HKO) mice treated with diet...

Deubiquitination of ME1 by OTUD7B promotes aerobic glycolysis of esophageal can…

Guan(L),Li(X),Du(Z),Yuan(Q),Zhou(F),Li(X),Xu… Biochem Pharmacol 2026-08-11

...ME1 to EC growth via aerobic glycolysis remains unclear. This study aimed to investigate the role of ME1 in EC and the u...

A cryptic allosteric pocket shapes isoform-selective inhibition of human malic …

Krinkel(BA),Yosaatmadja(Y),Slayton(MD),Krink… Protein Sci 2026-09-00

...ME1-3), suggesting that selectivity must arise elsewhere than the active site. Here, we define matched kinetic and regul...

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