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Exosomal Rspondin3 serves as a master regulator of immunometabolic repair in ...

Fang(B),Long(D),Li(T),Fu(H),Dong(Y),Tian(Y... Int Immunopharmacol 2026-05-01

...Rspo3) as the critical mediator in endothelial progenitor cell-derived exosomes (EPC-Exo) that coordinately regulates ma...

Nanopore long-read RNA sequencing reveals key genes regulating pre-hierarchic...

Cao(X),Xu(W),Zhang(H),Zhang(J),Jiang(Y),Li... Poult Sci 2026-05-00

...RSPO3, and WIF1). Moreover, RSPO3 upregulated the expression of FSHR and StAR in cultured chicken Pre-hierarchical folli...

Mesenchymal R-spondin 3 promotes an immunogenic tumor microenvironment with a...

Fischer(AS),Arnold(A),Berger(H),Müllerke(S... Gastric Cancer 2026-08-24

...RSPO3 expression with tumor inflammation, tumor stage, and survival. To mechanistically explore the role of Rspo3 in imm...

Characterizing the impact of plasma protein levels on human brain structure a...

Ayubcha(C),Dennis(E),Bhattacharyya(U),John... medRxiv 2026-07-15

...RSPO3, ENPP2, BTN2A1, EIF2AK3, MRVI1, and OPLAH ) with significant direct effects on the risk of Alzheimer's disease, Pa...

Tumor Necrosis Factor Receptor 1 Regulates Colonic Mesenchymal Cell Diversity...

Gadeock(S),Girish(N),Liu(CY),Huang(Y),Das(... Cell Mol Gastroenterol Hepatol 2026-08-11

...Rspo3, Wnt2b, and Fgf2, alongside increased extracellular matrix and proliferative signaling pathways, particularly inte...

Age-dependent functional and transcriptional differences in intestinal mesenc...

Ayansola(H),Jin(Y) Front Cell Dev Biol None

...RSPO3 level was highest at Day 0, BMP4 and PDGFRα expression peaked at Day 7, and WNT and BMP antagonists (SFRP1 and GRE...

Bile duct tumor thrombus (intraductal polypoid growth)-positive intrahepatic ...

Mitsui(A),Esaki(M),Nara(S),Arai(Y),Nakamur... J Pathol 2026-05-00

...RSPO3 fusion gene was found in one LDT case. Intraglandular papillary and tubular proliferation is a unique and rare his...

NsPEFs-enriched ADSCs-EVs alleviate osteoarthritis via RSPO3-mediated dual pr...

Wang(Y),Gao(Y),Cao(Z),Dong(M),Shao(P),Fan(... Bioact Mater 2026-05-00

...RSPO3). We further unveiled a novel dual function of chondrocyte-derived RSPO3. It acted in an autocrine manner to enhan...

Deletion of Rspo1 or Rspo3 in the mesenchyme does not affect Wolffian duct ma...

Jia(S),Wilbourne(J),Fogarty(A),Bai(W),Zhao(F) MicroPubl Biol None

...Rspo3 in the Wolffian duct mesenchyme. Wolffian duct maintenance and morphogenesis was unaffected in either Rspo1 or Rsp...

Integrating bulk, single-cell, and spatial transcriptomics to identify a nove...

Xiang(L),Rao(J),Ma(A),Zhang(Y),Li(C),Xie(T... Front Immunol None

...RSPO3, TREM1, and VEGFA) . The PRG signature demonstrated robust prognostic predictive performance. It effectively disti...

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