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The chaperonin TRiC component Cct3 is required for axonal transport, myelinat...

Zhang(X),Zajt(KK),Palaz(T),Wang(L),Groß(M)... Cell Death Dis 2026-02-12

...TCP1 subunits 1-8 (CCT1-8), TRiC acts as a chaperone that is required for folding of 10% of proteome, including actin an...

CCT5 as a candidate biomarker in bladder cancer: functional validation and me...

Zhang(X),Fu(Y),Du(Y),Xiong(W),Wang(J),Zhan... Am J Cancer Res None

...TCP1 complex, has been implicated in the development of various malignancies. However, its role in bladder cancer remain...

CCT3 Enhances Lung Adenocarcinoma Progression by Promoting p53 Ubiquitination...

Liu(H),Mao(F),Zhang(Y),Chen(J),Fan(J),Huan... Medicina (Kaunas) 2026-08-01

...TCP1 complex (CCT/TRiC), an ATP-dependent molecular chaperone involved in protein folding and proteostasis. Materials an...

CCT2 defines a highly cisplatin-resistant and poor-prognosis subtype of lung ...

Mao(H),Su(C),Han(X),Wang(G) Oncol Lett 2026-10-00

...TCP1 subunit 2 (CCT2) emerging as a key regulator of cisplatin resistance. Single-cell analyses showed that CCT2 was pre...

CCT2 Promotes Prostate Cancer Progression Through EIF3F-Dependent Stabilizati...

Xu(S),Zhang(Y),Li(H),Zhao(S),Dai(X),Xu(Q),... Adv Sci (Weinh) 2026-08-00

...TCP1 subunit 2 (CCT2) as a key oncogenic regulator that promotes lipid synthesis and enhances malignant phenotypes both ...

Serum and adipose tissue-derived extracellular vesicles as biomarker reservoi...

Heeran(AB),Hannon(G),Moran(B),Mhaonaigh(AU... Sci Rep 2026-06-25

...TCP1. Of these, HSP90AB1, CCT7, and TCP1 were significantly associated with poorer overall survival. These results highl...

Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcin...

Li(C),Yang(L),Zhang(Y),Zhao(B),Qu(H) Oncol Rep 2026-05-00

...TCP1) ring complex, chaperonin‑containing TCP1 subunit 2 (CCT2) participates in the development of numerous types of liv...

Chaperonin-mediated winter cold response via circadian clock components in Ar...

Jeong(G),Jeon(M),Kyung(J),Jeong(D),Shin(J)... New Phytol 2026-05-00

...TCP1 Ring Complex (TRiC)/Chaperonin Containing TCP1 (CCT) complex as a critical upstream regulator of both processes in ...

Hybrid Feature Selection-Based Machine Learning and Deep Learning Framework f...

Anumulapuri(S),Josyula(JVN),Pillai(AKB),Mu... Evol Bioinform Online None

...TCP1, HNRNPUL1, SEC14L5, ATP2C2, LOXL3, ACVRL1, STEAP3, and ST8SSIA5 as key discriminative features. Integrated network ...

Integrated bioinformatics and in vitro validation reveal the role of CCT5 in ...

Wang(B),Liu(X),Li(J),Dong(H),Fan(X),Wang(R... Discov Oncol 2026-04-28

...TCP1 Subunit 5 (CCT5) is recognized for its involvement in the oncogenesis and advancement of diverse malignancies, its ...

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