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Eosinophil major basic protein activates human cord blood mast cells primed wit…

Ben-Zimra(M),Bachelet(I),Seaf(M),Gleich(G J)… Allergy 2014-05-14

...Hck that further transduces the activation signal. MC priming with FBM leads to up-regulation in Hck protein level. MC i...

TNK2 gene amplification is a novel predictor of a poor prognosis in patients wi…

Shinmura(Kazuya),Kiyose(Shinichiro),Nagura(K… J Surg Oncol 2014-03-21

...HCK, SRC, and AURKA) in gastric cancer (GC). This study aimed to determine the prognostic significance of these gene amp...

HIV-1 infection of T cells and macrophages are differentially modulated by viri…

Cornall(Alyssa),Mak(Johnson),Greenway(Alison… Viruses 2014-03-07

...Hck into viral particles. Unexpectedly, wild-type Hck inhibited infection of macrophages, but Hck was shown to enhance i...

A novel mechanism of UV-A and riboflavin-mediated corneal cross-linking through…

Kopsachilis(Nikolaos),Tsaousis(Konstantinos … Cornea 2014-01-08

...HCK cells were treated with RFUV-A.,The enzymes tTgase and fibronectin are expressed by RFUV-A treatment in cultured HCK...

A novel interaction between the SH2 domain of signaling adaptor protein Nck-1 a…

Zhang(Guo),Chen(Xia),Qiu(Fanghua),Zhu(Fengxi… J Biol Chem 2014-12-16

...Hck significantly enhanced Nck-1-ELMO1 interaction. Moreover, wild type Nck-1, but not R308K mutant, significantly augme...

Analysis of 5-lipoxygenase phosphorylation on molecular level by MALDI-MS.

Markoutsa(Stavroula),Sürün(Duran),Karas(Mich… FEBS J 2014-06-11

...HCK) and Yes. To analyze the phosphorylation state in the cellular context, we created stably 5-LO-transduced Mono Mac 6...

Combining radiotherapy with MEK1/2, STAT5 or STAT6 inhibition reduces survival …

Stegeman(Hanneke),Kaanders(Johannes H A M),V… Mol Cancer 2014-07-08

...Hck, and STAT6, were correlated with radiosensitivity in the panel of HNSCC lines. In combination with radiotherapy, inh...

Cytotoxic-T-lymphocyte antigen 4 receptor signaling for lymphocyte adhesion is …

Kloog(Yoel),Mor(Adam) Mol Cell Biol 2014-04-24

...Hck facilitates C3G phosphorylation. These findings point to C3G and Hck as promising potential therapeutic targets for ...

Activation of Src family tyrosine kinases by ferric ions.

Baldwin(Graham S),Lio(Daisy Sio-Seng),Ferran… Biochim Biophys Acta 2014-05-09

...Hck kinases, which had been stabilised in the inactive state by phosphorylation of the C-terminal regulatory tyrosine, w...

Discovery of a diaminoquinoxaline benzenesulfonamide antagonist of HIV-1 Nef fu…

Trible(Ronald P),Narute(Purushottam),Emert-S… Retrovirology 2014-07-07

...Hck and other Src-family tyrosine kinases. Nef binding induces constitutive Hck activation that may contribute to HIV pa...

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