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The deubiquitinase USP17 regulates the expression and activity of the oncogen...

Acevedo(M),Dô(F),El-Mortada(F),Tanguay(PL)... Oncogene 2026-03-00

...KRAS-induced cell proliferation. RNA sequencing and quantitative proteomic analysis of USP17-depleted CRC cells revealed...

Advances in immunotherapy for colorectal cancer: overcoming resistance in mis...

Keivany(MR),Shojae Asrami(E),Besharatloo(M... Cancer Cell Int 2026-02-19

...KRAS-G12C, BRAF, MEK inhibitors) with ICIs, neoantigen-based vaccines, oncolytic viruses, and microbiome manipulation. B...

The polyamine inhibitor SAM486A increases the efficacy of adagrasib in non-sm...

Martin-Martin(A),Chipón(C),Guzman-Kunstman... Biol Res 2026-02-19

...KRASG12C-mutant cell lines, with minimal effects on KRAS-wild-type cells. In an orthotopic mouse model using a KRASG12C/...

Interleukin-1β as target to induce synthetic lethality in KRAS mutant biliary...

Li(S),Shan(Y),Chen(T),Topatana(W),Juengpan... Clin Mol Hepatol 2026-04-00

...KRAS-mutant and KRAS-wild type BTC cell lines, patient-derived xenografts (PDX), and KRAS oncogene-driven tumor models, ...

Interplay of Tumor Morphology and Biology with Postoperative Complications: P...

Altaf(A),Akabane(M),Tong(K),Khalil(M),Rash... Ann Surg Oncol 2026-05-00

...KRAS status, carcinoembryonic antigen levels, primary tumor lymph node metastasis, tumor burden score, and extrahepatic ...

KRAS-dependent glycolytic reprogramming of endothelial cells in sporadic arte...

Wu(R),Khosraviani(N),Mansur(A),Boudreau(E)... EMBO Mol Med 2026-03-00

Somatic activating KRAS mutations in endothelial cells are the predominant cause of sporadic brain arteriovenous malform...

Integration of TWAS with single-cell and spatial transcriptomics identifies T...

Zhang(J),Chen(Z) Int J Biol Macromol 2026-04-00

...Kras and TNFα. In the breast cancer TME, these genes are associated with myofibroblasts, mast cells, and M2 macrophages,...

Estrogen Receptor, GATA-3, TTF-1, and KRAS in Endometrial Carcinoma of No Spe...

Siili(E),Loukovaara(M),Bützow(R),Pasanen(A... Mod Pathol 2026-04-00

...KRAS in a large and relatively unselected NSMP carcinoma cohort. POLE sequencing results and immunohistochemistry for p5...

Clinico-genomic characterization of RAS-mutant acute myeloid leukemia.

Yuan(R),Xie(Y),Miron(PM),Higgins(AW),Hutch... Ann Hematol 2026-02-09

...KRAS vs. double-mutant) or among hotspot codons. Analysis of variant allele frequencies suggested that NRAS/KRAS mutatio...

Spectral CT imaging in colorectal cancer: current applications, limitations, ...

Grange(R),Wagner(M),Benzerdjeb(N),Glehen(O... Insights Imaging 2026-02-09

...KRAS mutation, Ki-67 index, microsatellite instability, lymphovascular, perineural, and extramural vascular invasion, as...

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