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Simple purification of highly active biotinylated P-glycoprotein: enantiomer-sp…

Julien(M),Kajiji(S),Kaback(R H),Gros(P) Biochemistry 2000-01-28

...Pgp (Pgp-H6BD). The expression/purification protocol for Pgp-H6BD involves high-level expression of the fusion protein i...

Developmental expression of P-glycoprotein (multidrug resistance gene product) …

Matsuoka(Y),Okazaki(M),Kitamura(Y),Taniguchi… J Neurobiol 1999-07-20

...PGP was found in cancer cells, but it is now known that PGP is richly distributed in the adult brain. Passage to the cen...

Ontogeny of P-glycoprotein in mouse intestine, liver, and kidney.

Mahmood(B),Daood(M J),Hart(C),Hansen(T W),Wa… J Investig Med 2001-06-07

...Pgp substrates. Little is known regarding the ontogeny of Pgp expression in these tissues.,Postnatal expression of Pgp o...

An MDR-EGFP gene fusion allows for direct cellular localization, function and s…

Pétriz(Jordi),Gottesman(Michael M),Aran(Jose… Curr Drug Deliv 2006-01-06

...Pgp-EGFP, we confirmed the stable nature of Pgp (t(1/2 total Pgp-EGFP) = 2.2 days), but revealed that surface-Pgp acquir...

Characterization of a new antibody raised against the NH2 terminus of P-glycopr…

Rao(Prema S),Govindarajan(Rajgopal),Mallya(K… Clin Cancer Res 2005-12-21

...Pgp) in these cancer cells. Thus, a prechemotherapy evaluation of Pgp in cancer cells aids in the design of alternative ...

Gefitinib, an EGFR tyrosine kinase inhibitor, directly inhibits the function of…

Kitazaki(Takeshi),Oka(Mikio),Nakamura(Yoichi… Lung Cancer 2006-02-23

...Pgp. We used multidrug resistant PC-6/PTX lung cancer and MCF-7/Adr breast cancer cells which overexpress Pgp and measur...

Marked differences in the effect of antiepileptic and cytostatic drugs on the f…

Alms(Dana),Fedrowitz(Maren),Römermann(Kersti… Pharm Res 2015-01-05

...Pgp in BCECs. Several older AEDs that induce human cytochrome P450 enzymes also induce Pgp in hepatocytes and enterocyte...

Characterization of a 95,000 molecule on sheep leucocytes homologous to murine …

Mackay(CR),Maddox(JF),Wijffels(GL),Mackay(IR… Immunology 1988-09-00

...Pgp-1 mAb that cross-reacts with human Pgp-1, established the specificity of 25-32 for human and sheep Pgp-1. Moreover, ...

P-glycoprotein expression on acute myeloid leukaemia blast cells at diagnosis p…

Wood(P),Burgess(R),MacGregor(A),Yin(J A) Br J Haematol 1995-01-13

...Pgp positive group than in the Pgp negative group (60% v 92%; P = 0.02). The overall survival for Pgp-positive patients ...

Topological folding and proteolysis profile of P-glycoprotein in membranes of m…

Zhang(M),Wang(G),Shapiro(A),Zhang(J T) Biochemistry 1996-09-10

...Pgp has been investigated. However, the results are in dispute. A major question concerning the Pgp topology is the memb...

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