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Cooperative regulation of neurotransmitter release by Rab3a and synapsin II.

Coleman(William L),Bykhovskaia(Maria) Mol Cell Neurosci 2010-08-02

...Rab3a. We found that Rab3a deletion rescued epileptic-like seizures typical for synapsin II gene deleted animals (Syn II...

Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapp...

Pavlos(Nathan J),Grønborg(Mads),Riedel(Die... J Neurosci 2010-10-29

...Rab3a, Rab3b, Rab3c, and Rab27b) and endocytic (Rab4b, Rab5a/b, Rab10, Rab11b, and Rab14) Rab machinery of SVs. Analysis...

Characterization of the intracellular localization, processing, and secretion...

Lonka-Nevalaita(Liina),Lume(Maria),Leppäne... J Neurosci 2010-09-16

...Rab3A-positive vesicles of the regulated secretory pathway. In addition, we find that matrix metalloproteinases and plas...

Metallothioneins and cancer.

Eckschlager(Tomas),Adam(Vojtech),Hrabeta(J... Curr Protein Pept Sci 2009-12-11

...Rab3A. New biological roles for these proteins have been identified including those needed in the carcinogenic process. ...

Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein...

Ishibashi(Koutaro),Kanno(Eiko),Itoh(Takash... Genes Cells 2009-04-10

...Rab3A in living cells and promoted the GTPase activity of Rab3A in vitro. Unexpectedly, however, FLJ13130 also promoted ...

Selective reduction in synaptic proteins involved in vesicle docking and sign...

Leitch(Beulah),Shevtsova(Olga),Kerr(John R... J Comp Neurol 2009-01-15

...Rab3a) but not of plasma membrane-associated protein (SNAP-25) in the terminals of the BDNF-deficient granule cells. Cha...

Rosuvastatin induces delayed preconditioning against oxygen-glucose deprivati...

Domoki(Ferenc),Kis(Béla),Gáspár(Tamás),Sni... Am J Physiol Cell Physiol 2009-02-26

...Rab3a protein levels. In conclusion, RST preconditions cultured neurons against OGD via depletion of GGPP, leading to de...

Loss of RAB-3/A in Caenorhabditis elegans and the mouse affects behavioral re...

Kapfhamer(D),Bettinger(J C),Davies(A G),Ea... Genes Brain Behav 2009-01-16

...Rab3A are resistant to the ataxic and sedative effects of ethanol, and Rab3A haploinsufficiency increases voluntary etha...

Role for Rab3a in oligodendrocyte morphological differentiation.

Anitei(Mihaela),Cowan(Ann E),Pfeiffer(Stev... J Neurosci Res 2009-03-25

...Rab3a overexpression and siRNAi-mediated Rab3a silencing. We found that Rab3a silencing delayed mature oligodendrocyte m...

Kinetics of Rab27a-dependent actions on vesicle docking and priming in pancre...

Merrins(Matthew J),Stuenkel(Edward L) J Physiol 2009-02-04

...Rab3a(-/-) mice exhibited complete refilling of the IRP and RRP, demonstrating that Rab27a and Rab3a exert distinct role...

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