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Biochemical properties of VGLL4 from Homo sapiens and Tgi from Drosophila melan…

Mesrouze(Y),Meyerhofer(M),Zimmermann(C),Font… Protein Sci 2021-00-00

...TEAD4/Sd at high protein concentrations. In solution, therefore, VGLL4/Tgi may predominantly interact with TEAD4/Sd via ...

TAZ promotes vasculogenic mimicry in gastric cancer through the upregulation of…

Zhang(Y),Bai(J),Cheng(R),Zhang(D),Qiu(Z),Liu… J Gastroenterol Hepatol 2022-04-00

...TEAD4 and their correlations with overall survival and VM-related markers were analyzed in 228 cases of GC. The regulato...

The YAP-TEAD4 inhibitor M511-0965 suppresses triple-negative breast cancer prog…

Cheng(M),Li(X),Song(N),Yang(X),Ma(X),Zhang(H… Transl Oncol 2026-09-00

...TEAD4 is highly expressed in TNBC, and its expression level influences the biological functions of TNBC. Thus, TEAD4 rep...

DNA-binding mechanism of the Hippo pathway transcription factor TEAD4.

Shi(Z),He(F),Chen(M),Hua(L),Wang(W),Jiao(S),… Oncogene 2017-00-27

...TEAD4 acts as a critical downstream effector of the evolutionarily conserved Hippo signaling pathway. The well-studied o...

Induction of a trophoblast-like phenotype by hydralazine in the p19 embryonic c…

O'Driscoll(CM),Coulter(JB),Bressler(JP) Biochim Biophys Acta 2013-03-00

...Tead4. A decrease in CpG methylation at three sites in the TEAD4 promoter and the B1 repeated sequence was observed. Kno...

TEAD4-mediated upregulation of LPAR3 augments hepatic stellate cell activation …

Qi(R),Chang(Z),Zhao(W),Qiu(Y),Chang(W),Zhang… Cell Biol Toxicol 2025-07-01

...TEAD4) in hepatic stellate cell (HSC) activation and portal hypertension (PHT) progression. LPAR3 exhibited heightened e...

Molecular design and rational optimization of synergistic effect between the tw…

Zhu(H),Xu(S),Wu(J),Hu(J),Mao(X) J Mol Recognit 2022-00-00

...TEAD4) transcription factor involved in the tumorigenesis of nasopharyngeal cancer. Previously, a parallel helix-helix i...

ZDHHC14-Mediated TEAD4 Palmitoylation Drives Th17 Cell Recruitment in Renal Imm…

Zhou(Y),Zhang(C),Xia(J),Shang(S),Liu(Q),Guo(… Research (Wash D C) 2025-00-00

...TEAD4, thereby facilitating Th17 cell recruitment. Notably, TEAD4 activity is regulated by palmitoylation modification r...

Hippo Pathway Dysregulation in Thymic Epithelial Tumors (TETs): Associations wi…

Elm(L),Gerlitz(N),Hochholzer(A),Papadopoulos… Int J Mol Sci 2025-06-20

...TEAD4 (p < 0.001) correlated with advanced stage. Cytoplasmic MST1 (p = 0.014), LATS1 (p < 0.001) and TEAD4 (p = 0.005) ...

Tead4 and Tfap2c generate bipotency and a bistable switch in totipotent embryos…

Zhu(M),Meglicki(M),Lamba(A),Wang(P),Royer(C)… Nat Struct Mol Biol 2024-06-00

...TEAD4 with activated RHOA accelerate embryo polarization. Here we show that these factors also accelerate the loss of to...

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