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Enveloped viruses disable innate immune responses in dendritic cells by direc...

Bhattacharyya(Suchita),Zagórska(Anna),Lew(... Cell Host Microbe 2014-03-10

...Tyro3/Axl/Mer (TAM) receptor tyrosine kinases promote phagocytic clearance of apoptotic cells and downregulate immune re...

Axl/Gas6/NFκB signalling in schwannoma pathological proliferation, adhesion a...

Ammoun(S),Provenzano(L),Zhou(L),Barczyk(M)... Oncogene 2014-03-14

TAM family receptor tyrosine kinases comprising Tyro3 (Sky), Axl, and Mer are overexpressed in some cancers, correlate w...

Autocrine role for Gas6 with Tyro3 and Axl in leiomyosarcomas.

el Sayadi(Hiba),Pissaloux(Daniel),Alberti(... Target Oncol 2014-09-17

...Tyro3. Gas6, a ligand of Tyro3, exerts an autocrine activities though Tyro3 and Axl in a subgroup of LMS.

Genome wide transcriptome analysis of dendritic cells identifies genes with a...

Filkor(Kata),Hegedűs(Zoltán),Szász(András)... PLoS One 2014-06-07

...Tyro3 and Mer are markedly downregulated in tolerant cells. We also demonstrate, that the expression pattern of TNFAIP3 ...

Flavivirus entry receptors: an update.

Perera-Lecoin(Manuel),Meertens(Laurent),Ca... Viruses 2014-08-01

...TYRO3, AXL and MER (TAM). Their role in flavivirus attachment and entry as well as their implication in the virus biolog...

TAM receptors affect adult brain neurogenesis by negative regulation of micro...

Ji(Rui),Tian(Shifu),Lu(Helen J),Lu(Qingjun... J Immunol 2014-02-18

...Tyro3(-/-)Axl(-/-)Mertk(-/-) triple-knockout (TKO) brains, consistent with the LPS-elicited enhanced expression of proin...

Axl receptor blockade ameliorates pulmonary pathology resulting from primary ...

Shibata(Takehiko),Habiel(David M),Coelho(A... J Immunol 2014-06-15

...Tyro3, Axl, and Mertk (TAM) receptor tyrosine kinases to infect and modulate the immune properties of various cell types...

TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis.

van der Meer(Jonathan H M),van der Poll(To... Blood 2014-06-05

...Tyro3, Axl, and Mer) belong to a family of receptor tyrosine kinases that have important effects on hemostasis and infla...

New aminopyrimidine derivatives as inhibitors of the TAM family.

Traoré(Ténin),Cavagnino(Andrea),Saettel(Ni... Eur J Med Chem 2014-09-19

...Tyro3 and Mer decreased to some extend. The preferential moderate inhibition of the non-phosphorylated form of Abl1 of s...

The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural ...

Paolino(Magdalena),Choidas(Axel),Wallner(S... Nature 2014-04-21

...Tyro3, Axl and Mer (also known as Mertk) were identified as ubiquitylation substrates for Cbl-b. Treatment of wild-type ...

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