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Complement C1Q polymorphisms modulate onset in familial amyloidotic polyneuro...

Dardiotis(Efthimios),Koutsou(Pantelitsa),Z... J Neurol Sci 2009-12-15

...APCS) and complement C1Q (A, B and C) genes was performed and APOE genotypes were determined. We searched for correlatio...

Functional consequences of Kv1.3 ion channel rearrangement into the immunolog...

Tóth(Agnes),Szilágyi(Orsolya),Krasznai(Zol... Immunol Lett 2009-09-24

...APC. In the present experiments we investigated the functional consequences of the translocation of Kv1.3 channels into ...

How the immune system achieves self-nonself discrimination during adaptive im...

Jiang(Hong),Chess(Leonard) Adv Immunol 2009-07-15

...APCs). We envision that the immune system achieves self-nonself discrimination, during adaptive immunity, not by recogni...

Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1...

Gao(Daming),Inuzuka(Hiroyuki),Korenjak(Mic... Mol Biol Cell 2009-10-13

APC/Cdh1 is a major cell cycle regulator and its function has been implicated in DNA damage repair; however, its exact r...

Risk of colorectal neoplasia associated with the adenomatous polyposis coli E...

Hall(M J),Liberman(E),Dulkart(O),Galazan(L... Ann Oncol 2009-11-09

Reports of the risk of colorectal neoplasia associated with a variant of the adenomatous polyposis coli (APC E1317Q) gen...

3,3'-diindolylmethane enhances the efficacy of butyrate in colon cancer preve...

Bhatnagar(Namrata),Li(Xia),Chen(Yue),Zhou(... Cancer Prev Res (Phila) 2009-08-21

...APC) gene confer resistance to HDAC inhibitor-induced apoptosis in colon cancers. Here, we show that APC mutation render...

Promoter methylation in APC, RUNX3, and GSTP1 and mortality in prostate cance...

Richiardi(Lorenzo),Fiano(Valentina),Vizzin... J Clin Oncol 2009-07-15

...APC (P = .047), GSTP1 (P = .002), and RUNX3 (P < .001). Methylation in APC was associated with an increased risk of pros...

An in vitro assay for Cdc20-dependent mitotic anaphase-promoting complex acti...

Schuyler(Scott C),Murray(Andrew W) Methods Mol Biol 2009-11-02

...APC), and a WD40-repeat protein co-factor called Cdc20. In vitro Cdc20-dependent APC (APC(Cdc20)) assays have been usefu...

Expression of beta-catenin and its mechanism of delocalization in intestinal-...

Lee(Soo Han),Kang(Hyun Jeong),Shin(Dong-Hu... Histol Histopathol 2009-08-19

...APC mutations in ICs. APC promoter hypermethylation was present in 49 of 105 (46.7%) cases of ICs. There was a significa...

Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease se...

Nath(Narender),Khan(Musfiquidin),Rattan(Ra... Biochem Biophys Res Commun 2009-07-27

...APCs), which are primarily involved in EAE disease progression. AMPK is lost at protein level in spleen macrophages, tot...

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