Zhao(Rong),Raub(Thomas J),Sawada(Geri A),K... Drug Metab Dispos 2009-09-25

...Bcrp1 stably transfected MDCKII cell monolayer transport studies demonstrated that each compound had affinity for Bcrp a...

Shen(Jun),Carcaboso(Angel M),Hubbard(K Ela... Cancer Res 2009-09-25

...Bcrp1(-/-), and Mdr1a/b(-/-)Bcrp1(-/-) mice were 3.07 +/- 0.09, 2.57 +/- 0.17, 1.63 +/- 0.12, and 0.86 +/- 0.05, respect...

Lyoumi(Said),Martin-Schmitt(Caroline),Toui... Chronobiol Int 2009-03-26

...Bcrp1 was also investigated. Male Wistar rats acclimatized to 12 h light (L): 12 h dark (D) cycles were sacrificed in th...

Xuan(Yanyan),Hu(Xun) Cancer Lett 2009-02-05

...BCRP1, by induction of necroptosis. The results strengthen the previous findings that necroptotic induction could circum...

Donnenberg(Vera S),Meyer(E Michael),Donnen... Methods Mol Biol 2009-11-12

...BCRP1). In this chapter, we will describe the complete procedure for the detection of MDR activity, including: (1) Prepa...

Polli(Joseph W),Olson(Katie L),Chism(John ... Drug Metab Dispos 2009-05-14

...Bcrp1(-/-), and Mdr1a/b(-/-)/Bcrp1(-/-) knockout mice. After an intravenous infusion of lapatinib for 24 h to a targeted...

Giri(Nagdeep),Agarwal(Sagar),Shaik(Naveed)... Drug Metab Dispos 2009-06-24

...Bcrp1/Abcg2). The selective BCRP inhibitor 3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino [1',2'...

Chen(Ying),Agarwal(Sagar),Shaik(Naveed M),... J Pharmacol Exp Ther 2009-09-21

...Bcrp1(-/-) mice. Dasatinib brain distribution was significantly increased in Mdr1a/b(-/-) mice and when wild-type mice w...

Dörner(Bernd),Kuntner(Claudia),Bankstahl(J... J Med Chem 2009-11-17

...Bcrp1((-/-)) mice (n = 3). In PET experiments in rats, administration of unlabeled 1 increased brain activity uptake 5.4...

Kitamura(Satoshi),Maeda(Kazuya),Wang(Yi),S... Drug Metab Dispos 2008-12-22

...Bcrp1 knockout mice were reduced to 53% and 12% of those in the control Sprague-Dawley rats and FVB mice, respectively, ...