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The homeodomain protein Cux1 interacts with Grg4 to repress p27 kip1 expressi...

Sharma(Madhulika),Brantley(Jennifer G),Vas... Gene 2009-06-11

...Cux1 in the presence of Grg4. Chromatin immunoprecipitation (ChIP) assays demonstrated the direct interaction of Cux1 wi...

Regulation of cell proliferation and differentiation in the kidney.

Alcalay(Neal I),Vanden Heuvel(Gregory B) Front Biosci (Landmark Ed) 2009-08-25

...Cux1 expression is developmentally regulated in multiple tissues suggesting an important regulatory function. Cux1 exist...

p110 CUX1 homeodomain protein stimulates cell migration and invasion in part ...

Kedinger(Valerie),Sansregret(Laurent),Hara... J Biol Chem 2009-10-21

...CUX1 transcription factor can stimulate cell migration and invasion. The full-length p200 CUX1 had a weaker effect than ...

Transcriptional activation of the Lats1 tumor suppressor gene in tumors of CU...

Siam(Rania),Harada(Ryoko),Cadieux(Chantal)... Mol Cancer 2009-10-20

...CUX1 in transgenic mice increases the susceptibility to cancer in various organs and tissues. In tissue culture, p110 CU...

Repression of human cytomegalovirus major immediate early gene expression by ...

Stern(J Lewis),Cao(John Z),Xu(Jiake),Mocar... Virology 2008-09-23

...CUX1 core binding sequence ATCGAT and mutagenesis of this sequence abrogated CUX1 binding. Furthermore, CUX1 repressed e...

p110 CUX1 cooperates with E2F transcription factors in the transcriptional ac...

Truscott(Mary),Harada(Ryoko),Vadnais(Charl... Mol Cell Biol 2008-05-14

...CUX1 was shown to stimulate cell proliferation by accelerating entry into S phase. As p110 CUX1 can function as a transc...

Polycystic kidneys caused by sustained expression of Cux1 isoform p75.

Cadieux(Chantal),Harada(Ryoko),Paquet(Mari... J Biol Chem 2008-07-09

...Cux1 (CDP, Cutl1) is aberrantly expressed in mouse models for polycystic kidney disease. Here we show that p75-Cux1, the...

Proteolytic processing of cut homeobox 1 by neutrophil elastase in the MV4;11...

Goulet(Brigitte),Markovic(Yelena),Leduy(La... Mol Cancer Res 2008-07-07

...CUX1) at the end of the G(1) phase, whereas an alternative transcript encodes p75 CUX1. These short CUX1 isoforms were r...

The multiple roles of CUX1: insights from mouse models and cell-based assays.

Sansregret(Laurent),Nepveu(Alain) Gene 2008-06-19

...CUX1 was originally characterized as the CCAAT-displacement protein (CDP). Another line of investigation revealed the pr...

Genome-wide location analysis and expression studies reveal a role for p110 C...

Harada(Ryoko),Vadnais(Charles),Sansregret(... Nucleic Acids Res 2008-02-15

...CUX1 transcription factor generates an isoform, p110 that accelerates entry into S phase. To identify targets of p110 CU...

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