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Tyrosine phosphorylation of Wiskott-Aldrich syndrome protein (WASP) by Hck regu…

Park(Haein),Dovas(Athanassios),Hanna(Samer),… J Biol Chem 2014-05-14

...Hck(-/-) BMMs or Hck shRNA cells. In particular, WASP phosphorylation was primarily mediated by the p61 isoform of Hck. ...

Kinase crystal identification and ATP-competitive inhibitor screening using the…

Parker(Lorien J),Taruya(Shigenao),Tsuganezaw… Acta Crystallogr D Biol Cryst… 2014-10-21

...HCK co-crystal structures confirmed that SKF86002 interacts with the ATP-binding sites of Pim1 and HCK. The structures o...

A novel mechanism of UV-A and riboflavin-mediated corneal cross-linking through…

Kopsachilis(Nikolaos),Tsaousis(Konstantinos … Cornea 2014-01-08

...HCK cells were treated with RFUV-A.,The enzymes tTgase and fibronectin are expressed by RFUV-A treatment in cultured HCK...

Activation of Src family tyrosine kinases by ferric ions.

Baldwin(Graham S),Lio(Daisy Sio-Seng),Ferran… Biochim Biophys Acta 2014-05-09

...Hck kinases, which had been stabilised in the inactive state by phosphorylation of the C-terminal regulatory tyrosine, w...

Analysis of 5-lipoxygenase phosphorylation on molecular level by MALDI-MS.

Markoutsa(Stavroula),Sürün(Duran),Karas(Mich… FEBS J 2014-06-11

...HCK) and Yes. To analyze the phosphorylation state in the cellular context, we created stably 5-LO-transduced Mono Mac 6...

A novel interaction between the SH2 domain of signaling adaptor protein Nck-1 a…

Zhang(Guo),Chen(Xia),Qiu(Fanghua),Zhu(Fengxi… J Biol Chem 2014-12-16

...Hck significantly enhanced Nck-1-ELMO1 interaction. Moreover, wild type Nck-1, but not R308K mutant, significantly augme...

The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the…

Kovács(Miklós),Németh(Tamás),Jakus(Zoltán),S… J Exp Med 2014-11-17

...Hck, Fgr, and Lyn in the hematopoietic compartment were completely protected from autoantibody-induced arthritis and ski...

mRNA expression of metabolic enzymes in human cornea, corneal cell lines, and h…

Kölln(Christian),Reichl(Stephan) J Ocul Pharmacol Ther 2013-01-16

...HCK-Ca) and human corneal endothelial cell line (HENC) were used. Human liver tissue, human corneal epithelium from dono...

Tyrosine kinase expression profile in clear cell renal cell carcinoma.

Behbahani(Turang E),Thierse(Claudia),Baumann… World J Urol 2013-03-29

...HCK using immunohistochemistry.,A total of 12 TK were significantly upregulated in ccRCC (ABL2, FLT1, BTK, HCK, JAK3, CS...

Screening and functional analysis of differentially expressed genes in EBV-tran…

Dai(Yongming),Tang(Yunlian),He(Fei),Zhang(Ya… Virol J 2013-01-11

...HCK, CD247, PRKCQ, ITK, LCP2, CXCL1, CD8A, ITGB5, VAV3, CXCR4), which primarily control biological processes such as cel...

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