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Molecular Pathogenesis and Targeted Therapies for Myeloproliferative Hypereos...

Hanna(C),Rizkallah(J),Charbel(N),Sakkal(S)... Curr Hematol Malig Rep 2026-03-07

...PDGFRA/B-rearranged disease, resistance has spurred the development of next-generation inhibitors like avapritinib, whic...

Computational Identification and Validation of PDGFRA and HIF1A as Direct Tar...

Chen(Y),Zhu(ZJ) Transplant Proc 2026-04-00

...PDGFRA, which was further confirmed by stable binding in MD simulations. Human Protein Atlas data indicated specific exp...

Gene Mutations and Related Molecular Events in Distant Metastasis of Cervical...

Guo(Y),Li(S),Liu(T),Chang(X),Qin(P),Wang(N... Int J Med Sci None

...PDGFRA, TP53, and PIK3CA mutations significantly influence metastasis. Despite its low incidence, PDGFRA mutation is clo...

The IL-10/IL-10Rα axis in fibroblasts limits large intestinal pathology by su...

Ito(T),Li(B),Sakaguchi(T),Yagita-Sakamaki(... Int Immunol 2026-05-13

...Pdgfra-cre; Il10raf/f mice aged 16 weeks or older develop chronic spontaneous colitis and subsequent fibrosis accompanie...

Hypereosinophilic endocarditis presenting with intracardiac mass and severe m...

Rao(NS),Biswas(A),Kothari(SS),Vyas(P),Kana... Eur Heart J Case Rep 2026-05-00

...PDGFRA fusion, confirming a myeloid neoplasm with hypereosinophilia. The patient was treated with corticosteroids, antic...

Myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions...

Luo(R),Qi(X) BMC Neurol 2026-05-14

...PDGFRA fusion, leading to a diagnosis of MLN-TK with FIP1L1::PDGFRA. Treatment with low-dose imatinib (100 mg daily) and...

Multiomic Landscape of Gastrointestinal Stromal Tumors in a Real-World Patien...

Serrano(C),Elliott(A),Gómez-Peregrina(D),E... Clin Cancer Res 2026-08-14

...PDGFRA-mutant, and KIT/PDGFRA-WT. These alterations can be captured only by using next-generation sequencing technologie...

Analysis of Somatic Mutations and Immunotherapy Biomarkers in Chinese Patient...

Liu(X),Chen(W),Xin(C),Wang(Z),Yi(K),Wang(L... Health Sci Rep 2026-05-00

...PDGFRA and MET, or NRAS and PTEN in A549 cells, promoted cell proliferation and invasion compared with the control cells...

TRIM21 drives glioblastoma malignancy via ubiquitination-mediated PDGFRA degr...

Gai(QJ),Wang(C),Li(SD),Pang(B),Sun(Q),Zhou... Cancer Lett 2026-08-10

...PDGFRA. We demonstrated that TRIM21 catalyzed K48-linked polyubiquitination specifically at lysine 606 of PDGFRA, direct...

Integrative In Silico and FFPE Tissue Analyses Elucidate Upregulated Genes in...

Ali(EAM),Altaie(AM),Alhamidi(RS),Ali(N),Bo... Int J Mol Sci 2026-04-19

...PDGFRA), CBP/p300-interacting transactivator with glutamic acid/aspartic acid-rich carboxyl-terminal domain 2 (CITED2), ...

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