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Selective reduction in synaptic proteins involved in vesicle docking and sign...

Leitch(Beulah),Shevtsova(Olga),Kerr(John R... J Comp Neurol 2009-01-15

...Rab3a) but not of plasma membrane-associated protein (SNAP-25) in the terminals of the BDNF-deficient granule cells. Cha...

Metallothioneins and cancer.

Eckschlager(Tomas),Adam(Vojtech),Hrabeta(J... Curr Protein Pept Sci 2009-12-11

...Rab3A. New biological roles for these proteins have been identified including those needed in the carcinogenic process. ...

PTP1B dephosphorylates N-ethylmaleimide-sensitive factor and elicits SNARE co...

Zarelli(Valeria E P),Ruete(Maria C),Rogger... J Biol Chem 2009-06-18

...Rab3A, alpha-SNAP, N-ethylmaleimide-sensitive factor (NSF), SNAREs, complexin, and synaptotagmin VI. We report here that...

Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein...

Ishibashi(Koutaro),Kanno(Eiko),Itoh(Takash... Genes Cells 2009-04-10

...Rab3A in living cells and promoted the GTPase activity of Rab3A in vitro. Unexpectedly, however, FLJ13130 also promoted ...

Rab3a-mediated vesicle recruitment regulates short-term plasticity at the mou...

Coleman(William L),Bykhovskaia(Maria) Mol Cell Neurosci 2009-07-28

...Rab3a deficiency in maintaining the releasable pool. Rab3a(-) terminals demonstrated a small but significant low-frequen...

Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis.

Branham(María T),Bustos(Matías A),De Blas(... J Biol Chem 2009-11-02

...Rab3A. Recombinant Epac does not release GDP from Rab3A in vitro, suggesting that the Rab3A-GEF activation by cAMP/Epac ...

Wnt signaling mediates experience-related regulation of synapse numbers and m...

Gogolla(Nadine),Galimberti(Ivan),Deguchi(Y... Neuron 2009-06-15

...Rab3a promoted LMT volume growth. In parallel, EE increased postsynaptic CA3 pyramidal neuron Wnt7a/b levels. Inhibiting...

APP anterograde transport requires Rab3A GTPase activity for assembly of the ...

Szodorai(Anita),Kuan(Yung-Hui),Hunzelmann(... J Neurosci 2009-12-11

...Rab3A, and a specific subset of presynaptic protein components. Moreover, we report that assembly of kinesin-1C and APP ...

Kinetics of Rab27a-dependent actions on vesicle docking and priming in pancre...

Merrins(Matthew J),Stuenkel(Edward L) J Physiol 2009-02-04

...Rab3a(-/-) mice exhibited complete refilling of the IRP and RRP, demonstrating that Rab27a and Rab3a exert distinct role...

Herpes simplex virus utilizes the large secretory vesicle pathway for anterog...

Miranda-Saksena(Monica),Boadle(Ross A),Agg... J Virol 2009-03-30

...Rab3A, SNAP-25, GAP-43, and kinesin-1, involved in the secretory and exocytic pathways in axons. These proteins were als...

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