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Hyperactive mTORC1 signaling is unaffected by metformin treatment in aged ske...

Dungan(Cory M),Li(Zhuyun),Wright(David C),... Muscle Nerve 2016-05-16

...rpS6 phosphorylation in the young.,Collectively, these data suggest metformin is ineffective at normalizing growth signa...

Dual inhibition of EGFR and MET induces synthetic lethality in triple-negativ...

Yi(Yong Weon),You(Kyusic),Bae(Edward Jeong... Int J Oncol 2016-03-21

...RPS6) in MSL subtype TNBC cells. In addition, knockdown of RPS6 itself, in both HS578T and MDA-MB‑231, markedly reduced ...

Low dose of IGF-I increases cell size of skeletal muscle satellite cells via ...

Gao(Chun-qi),Zhi(Rui),Yang(Zhou),Li(Hai-ch... J Cell Biochem 2016-06-14

...rpS6 (Ser235/236), whereas PF4708671 lowered the protein level of p-S6K (Thr389) and p-rpS6 (Ser235/236). However, low d...

Response to dual HER2 blockade in a patient with HER3-mutant metastatic breas...

Bidard(F-C),Ng(C K Y),Cottu(P),Piscuoglio(... Ann Oncol 2016-04-21

...rpS6 and phospho-AKT in the post-therapy biopsy of the liver metastasis.,This is the first-in-man evidence that anti-HER...

Fine mapping of barley locus Rps6 conferring resistance to wheat stripe rust.

Li(Kun),Hegarty(Joshua),Zhang(Chaozhong),W... Theor Appl Genet 2016-07-22

...Rps6. The detection of the same locus in the cultivated barley 'Tamalpais' and in the Chinese barley 'Y12' by an allelis...

Phenotypically Dormant and Immature Leukaemia Cells Display Increased Ribosom...

Pallis(Monica),Harvey(Tamsin),Russell(Nige... PLoS One 2016-08-03

...rpS6 was 22-fold higher. Moreover, in contrast to 4E-BP1, rpS6 phosphorylation was higher in dormant than proliferating ...

Data on intracellular localization of RPSA upon alteration of its redox state...

Vilas-Boas(Filipe),Bagulho(Ana),Jerónimo(A... Data Brief 2016-02-10

...RPS6) was performed in cells overexpressing RPSAwt or RPSAmut. Finally, the ribosomal expression of endogenous RPSA in t...

Isolation and fine mapping of Rps6: an intermediate host resistance gene in b...

Dawson(Andrew M),Ferguson(John N),Gardiner... Theor Appl Genet 2016-07-22

...Rps6. We used phenotypic and genotypic selection on F2:3 families to isolate Rps6 and fine mapped the locus to a 0.1 cM ...

Phosphorylation of ribosomal protein S6 mediates compensatory renal hypertrophy.

Xu(Jinxian),Chen(Jianchun),Dong(Zheng),Mey... Kidney Int 2016-01-26

...rpS6) knock-in mice expressing nonphosphorylatable rpS6 and found that uninephrectomy-induced renal hypertrophy was sign...

Adaptations to chronic rapamycin in mice.

Dodds(Sherry G),Livi(Carolina B),Parihar(M... Pathobiol Aging Age Relat D... 2016-05-30

...rpS6) in colon and fat. However, in colon, contrary to expectations, there was an upregulation of 18S rRNA and some ribo...

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