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Whole-exome sequencing identifies de novo mutation in the COL1A1 gene to underl…

Maasalu(Katre),Nikopensius(Tiit),Kõks(Sulev)… Hum Genomics 2016-01-08

...COL1A1 gene. The aim of the present study is to describe the phenotype of OI II patient and a novel mutation, causing cu...

[Establishment and application of a high-throughput drug screening model based …

Zhao(Shuang-Shuang),Wang(Ju-Xian),Wang(Yu-Ch… Yao Xue Xue Bao 2016-02-02

...COL1A1 promoter. The activity of COL1A1 promoter and luciferase reporter gene can be elevated by TGF-β1, and inhibited b...

Identification of a novel TGF-β-miR-122-fibronectin 1/serum response factor sig…

Zeng(Chunxian),Wang(Yun-Long),Xie(Chen),Sang… Oncotarget 2016-04-05

...COL1A1), in HSCs and fibroblasts. Subsequent mechanism investigations revealed that miR-122 directly inhibited FN1 expre...

Molecular Outcome, Prediction, and Clinical Consequences of Splice Variants in …

Schleit(Jennifer),Bailey(Samuel S),Tran(Thao… Hum Mutat 2016-03-22

...COL1A1. All individuals with IVSX-1G>A mutations had OI type I because the substitution shifted the splice acceptor site...

An ex vivo model for studying hepatic schistosomiasis and the effect of release…

Gobert(Geoffrey N),Nawaratna(Sujeevi K),Harv… PLoS Negl Trop Dis 2016-02-18

...COL1A1 expression by qPCR after 24 hrs culture. Cytokine and chemokine analysis of the culture supernatants confirmed th...

Mechanical Tension Promotes the Osteogenic Differentiation of Rat Tendon-derive…

Liu(Xiangzhou),Chen(Wan),Zhou(You),Tang(Kang… Cell Physiol Biochem 2016-02-25

...Col1a1 and increased Runx2 protein expression. Wnt5a, Wnt5b and P-JNK protein levels were also upregulated after UMT sti...

CCN5 attenuates profibrotic phenotypes of fibroblasts through the Smad6-CCN2 pa…

Xu(Honghai),Liu(Cong),Sun(Zhengming),Guo(Xio… Int J Mol Med 2016-03-24

...COL1A1) and total collagen concentrations. Additionally, CCN5 over-expression decreased CCN2 expression and increased Sm...

[The study of rs1800012 polymorphism of the alphal-chain collagen type 1 gene i…

Shilina(N M),Sorokina(E Yu),Ivanushkina(T A)… Vopr Pitan 2016-02-23

...COL1A1) was studied by real-time PCR in 422 Moscow women and children, including pregnant women (n=96), lactating (n=29)...

Gossypol ameliorates liver fibrosis in diabetic rats induced by high-fat diet a…

Chen(Guorong),Wang(Rongrong),Chen(Hanbin),Wu… Life Sci 2016-07-28

...Col1a1), collagen III (Col3a1), fibronectin (Fn1), tissue inhibitor of metalloproteinase 1 (Timp1), and 2 (Timp2) were m...

COX-2 modulates mammary tumor progression in response to collagen density.

Esbona(Karla),Inman(David),Saha(Sandeep),Jef… Breast Cancer Res 2016-10-07

...Col1a1 (tm1jae) , there is accelerated mammary tumor formation and progression. Previous gene expression analysis sugges...

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