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Investigation of the role of breast cancer resistance protein (Bcrp/Abcg2) on...

Giri(Nagdeep),Shaik(Naveed),Pan(Guoyu),Ter... Drug Metab Dispos 2008-09-26

...Bcrp1 on plasma pharmacokinetics and brain penetration of zidovudine and abacavir in wild-type and Bcrp1-deficient (Bcrp...

In vitro transport of gimatecan (7-t-butoxyiminomethylcamptothecin) by breast...

Marchetti(Serena),Oostendorp(Roos L),Pluim... Mol Cancer Ther 2008-03-19

...Bcrp1, MDCKII-MDR1, and MDCKII-MRP2), and LLCPK (LLCPK-WT and LLCPK-MDR1) cells. Competition with methotrexate uptake wa...

The breast cancer resistance protein (Bcrp1/Abcg2) limits fetal distribution ...

Zhou(Lin),Naraharisetti(Suresh Babu),Wang(... Mol Pharmacol 2008-04-07

...Bcrp1 cells. GLB was also shown to be a BCRP/Bcrp1 substrate in transwell transport experiments. We then examined whethe...

P-glycoprotein limits oral availability, brain penetration, and toxicity of a...

Lagas(Jurjen S),Sparidans(Rolf W),van Wate... Antimicrob Agents Chemother 2008-09-02

...Bcrp1. Using P-gp-deficient mice, we found a marked increase in plasma salinomycin concentrations after oral administrat...

Drug-resistant AML cells and primary AML specimens are killed by 111In-anti-C...

Kersemans(Veerle),Cornelissen(Bart),Minden... J Nucl Med 2008-10-27

...BCRP1, or MRP1 transporters. Targeted Auger electron radioimmunotherapy using (111)In-labeled anti-CD33 monoclonal antib...

Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 ...

Marchetti(Serena),de Vries(Nienke A),Buckl... Mol Cancer Ther 2008-10-22

...Bcrp1/Mdr1a/1b(-/-) (triple-knockout) and WT mice. In vitro, erlotinib was actively transported by P-gp and BCRP/Bcrp1. ...

Breast cancer resistance protein 1 limits fetal distribution of nitrofurantoi...

Zhang(Yi),Wang(Honggang),Unadkat(Jashvant ... Drug Metab Dispos 2008-01-03

...Bcrp1, the murine homolog of human BCRP, limits fetal distribution of the model BCRP/Bcrp1 substrate, nitrofurantoin (NF...

P-glycoprotein and breast cancer resistance protein: two dominant transporter...

de Vries(Nienke A),Zhao(Jin),Kroon(Emily),... Clin Cancer Res 2008-01-22

...Bcrp1(-/-), and compound Mdr1a/b(-/-)Bcrp1(-/-) knockout mice. Drug levels in plasma and tissues were determined by high...

Erythroblasts highly express the ABC transporter Bcrp1/ABCG2 but do not show ...

Yamamoto(Kazumi),Suzu(Shinya),Yoshidomi(Yu... Immunol Lett 2008-01-14

...Bcrp1/ABCG2, erythroblasts did not show the "side population" phenotype. Furthermore, a Bcrp1/ABCG2 inhibitor, verapamil...

MDR1 and BCRP1 expression in leukemic progenitors correlates with chemotherap...

Ho(Maria M),Hogge(Donna E),Ling(Victor) Exp Hematol 2008-05-20

...BCRP1, two ABC transporters associated with drug resistance, was found in 8 of 10 NR patients as compared to 0 of 7 CR p...

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