...COL1A2 and CXCL8 highlighted as hub genes. Additionally, specific genes such as NTRK2, JUN, LAT, and DRD2 were identifie...
...COL1A2 in 40 cases, IFITM5 in 3, SERPINF1 in 1, and BMP1 in 1. Of the OI patients, 18 (40%) were in the overweight or ob...
...COL1A2, ESR1, PDGFRA, LUM and BCL2 as central hub genes. Molecular docking demonstrated favourable binding interactions ...
...COL1A2, and COL3A1) and actin alpha 2, smooth muscle, without affecting cell proliferation, apoptosis, or migration. Tra...
...COL1A2, TIMP1, CTGF, MMP2, and TGFβ) along with increased collagen deposition. In contrast, TNFα and IFNγ suppressed fib...
...COL1A2, COL3A1, COL5A1, COL5A2, SPARC, LOX, and LOXL2, indicating reinforced matrix deposition and crosslinking. Metallo...
Pathogenic variants in COL1A1 and COL1A2 account for 85-90% of osteogenesis imperfecta (OI). Glycine substitutions withi...
...COL1A2), indicative of active extracellular matrix remodeling. Pathway analysis identified enrichment in peroxisome acti...
...Col1a2-CreERT2 and Postn-CreERT2 drivers. The model of renal fibrosis was established by unilateral ureteral obstruction...
...Col1a2), and Sphingomyelin phosphodiesterase 3 (Smpd3), was downregulated by ethanol, with stronger ethanol-mediated red...
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