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Bioinformatics-driven discovery and experimental validation of differentially...

Kolour(HR),Sarirchi(S),Zamani(B),Daskar-Ab... Mol Biol Rep 2026-07-28

...COL1A2 and CXCL8 highlighted as hub genes. Additionally, specific genes such as NTRK2, JUN, LAT, and DRD2 were identifie...

[Obesity characteristics and body composition in children with osteogenesis i...

Xu(XQ),Zheng(JP),Zhou(XL),Lin(H),Chen(XF),... Zhonghua Er Ke Za Zhi 2026-08-02

...COL1A2 in 40 cases, IFITM5 in 3, SERPINF1 in 1, and BMP1 in 1. Of the OI patients, 18 (40%) were in the overweight or ob...

Systems-level identification of conserved molecular drivers underlying the pr...

Nandagopal(PB),Munieswaran(G),Manickam(V) Front Bioinform None

...COL1A2, ESR1, PDGFRA, LUM and BCL2 as central hub genes. Molecular docking demonstrated favourable binding interactions ...

Adipose-derived stem cell peptide 5 alleviates hypertrophic scarring through ...

Chen(L),Zhang(E),Zeng(S),Yan(Q),Li(J),Li(Q... Burns Trauma None

...COL1A2, and COL3A1) and actin alpha 2, smooth muscle, without affecting cell proliferation, apoptosis, or migration. Tra...

Targeting canonical TGFβ/SMAD3 and ERK1/2 signaling in human valve interstiti...

Ramireddi(CS),Rai(MK),Singh(A),Agarwal(V),... J Physiol Biochem 2026-07-16

...COL1A2, TIMP1, CTGF, MMP2, and TGFβ) along with increased collagen deposition. In contrast, TNFα and IFNγ suppressed fib...

Distinct Molecular Signature of Earlobe Keloids: Integrated Transcriptomic An...

Tafner(D),Naccarato(AM),Isoldi(FC),Felix(G... Aesthetic Plast Surg 2026-07-07

...COL1A2, COL3A1, COL5A1, COL5A2, SPARC, LOX, and LOXL2, indicating reinforced matrix deposition and crosslinking. Metallo...

Complexity of genomic diagnosis: Lessons learnt from the UK Biobank and Gener...

Sethuraman(C),Keigwin(S),Delaney(S),Makino... Bone 2026-11-00

Pathogenic variants in COL1A1 and COL1A2 account for 85-90% of osteogenesis imperfecta (OI). Glycine substitutions withi...

Multiomic data integration unveils molecular mechanisms underlying chestnut a...

Chen(W),Liu(J),Ullah(A),Dou(M),Peng(Y),Kha... BMC Genomics 2026-07-13

...COL1A2), indicative of active extracellular matrix remodeling. Pathway analysis identified enrichment in peroxisome acti...

Genetic and pharmaceutical targeting of Suv39h1 ameliorates renal fibrosis by...

Wu(X),Luo(Y),Wu(C),Ni(J),Xu(Y),Kong(M),Zha... J Adv Res 2026-08-10

...Col1a2-CreERT2 and Postn-CreERT2 drivers. The model of renal fibrosis was established by unilateral ureteral obstruction...

Aging Exacerbates Binge Ethanol-Mediated Bone Toxicity in Mice.

Pedersen(KB),Bordelon(M),Baker(E),Luo(M),T... Alcohol Clin Exp Res (Hoboken) 2026-08-00

...Col1a2), and Sphingomyelin phosphodiesterase 3 (Smpd3), was downregulated by ethanol, with stronger ethanol-mediated red...

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