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Impaired neural circuitry of hippocampus in Pax2 nervous system-specific knocko…

Wang(Y),Wang(Y),Tang(J),Li(R),Jia(Y),Yang(H)… CNS Neurosci Ther 2024-00-00

...Pax2 in RRBs. In this study, Pax2 nervous system-specific knockout mice (Nestin-Pax2 mice) aged 6-8 weeks and Pax2 flox ...

Ocular manifestations of the genetic causes of focal and segmental glomeruloscl…

Zhu(V),Huang(T),Wang(D),Colville(D),Mack(H),… Pediatr Nephrol 2024-03-00

...PAX2 but not PLCE1) may have ocular manifestations . Many genes affected in childhood-adolescent onset FSGS (NPHS1, NPHS...

Ocular manifestations of congenital anomalies of the kidney and urinary tract (…

Virth(J),Mack(HG),Colville(D),Crockett(E),Sa… Pediatr Nephrol 2024-02-00

...PAX2, EYA1, SALL1, GATA3, PBX1) that represent 30% of all diagnoses had ocular features. The ocular abnormalities found ...

Metabolomics and transcriptomics analysis of prefrontal cortex in the Pax2 neur…

Li(R),Tang(J),Wang(Y),Wang(Y),Yang(H),Wei(H) Prog Neuropsychopharmacol Bio… 2024-01-10

...Pax2 heterozygous gene knockout mice (Pax2+/- KO mice) exhibit significantly increased self-grooming, which suggests tha...

What Is Hidden in Patients with Unknown Nephropathy? Genetic Screening Could Be…

Mitrotti(A),Di Bari(I),Giliberti(M),Franzin(… Int J Mol Sci 2024-01-24

...PAX2: c.1266dupC) in three family members with different clinical diagnoses. Interestingly we also found one female pati...

PAX2 mediated upregulation of ESPL1 contributes to cisplatin resistance in blad…

Zhang(W),Wang(Y),Tang(Q),Li(Z),Sun(J),Zhao(Z… Naunyn Schmiedebergs Arch Pha… 2024-00-00

...PAX2 siRNA (si-PAX2) or overexpression vector (pcDNA-PAX2), and then treated with DDP or AG490, an inhibitor of JAK2. Th...

Monocytes prevent apoptosis of iPSCs and promote differentiation of kidney orga…

Pecksen(E),Tkachuk(S),Schröder(C),Vives Enri… Stem Cell Res Ther 2024-00-03

...Pax2) and GATA Binding Protein 3 (Gata3) was assessed by RT-PCR and western blotting. Organoids were imaged by 3D-confoc...

Kidney Organoid Modeling of WT1 Mutations Reveals Key Regulatory Paths Underlyi…

Wang(G),Wu(H),Zhai(X),Zhang(L),Zhang(C),Chen… Adv Sci (Weinh) 2024-08-00

...PAX2/MAGI2 that regulates WNT signaling pathway, MYH9 that maintains actin filament organization and NPHS1 that modulate...

Lesions sub-diagnostic of endometrioid intra-epithelial neoplasia/atypical hype…

Wyvekens(N),Mutter(GL),Nucci(MR),Kolin(DL),P… Histopathology 2024-10-00

...PAX2, PTEN, beta-catenin) to predict outcome. Of 430 women with SL on endometrial sampling at Brigham and Women's Hospit...

PAX2 is Transcriptionally Silenced by a Distinct Mechanism of Epigenetic Reprog…

Sahoo(SS),Ramanand(SG),Cuevas(IC),Gao(Y),Lee… bioRxiv 2024-12-23

...PAX2 is expressed throughout normal endometrial glands; however, microscopic clones with PAX2 protein loss arise spontan...

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