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SOX1 functions as a tumor suppressor by antagonizing the WNT/β-catenin signal...

Tsao(Chun-Ming),Yan(Ming-De),Shih(Yu-Lueng... Hepatology 2013-02-28

...SOX1 was frequently downregulated through promoter hypermethylation in HCC cells and tissues. Overexpression of SOX1 by ...

Efficient neuronal differentiation and maturation of human pluripotent stem c...

Lu(Hong Fang),Lim(Sze-Xian),Leong(Meng Fat... Biomaterials 2013-03-12

...SOX1 and PAX6 than those in other treatment conditions. Immunocytochemisty analysis confirmed that the majority of the d...

DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis o...

Neely(M Diana),Litt(Michael J),Tidball(And... ACS Chem Neurosci 2013-08-27

...SOX1 expressing cells, whereas PAX6, another neural precursor marker, remained the same. The level and timing of SOX1 ex...

Zfhx1b induces a definitive neural stem cell fate in mouse embryonic stem cells.

Dang(Lan T H),Wong(Loksum),Tropepe(Vincent... Stem Cells Dev 2013-03-01

...Sox1 expression, a marker found in neural precursors and to promote definitive NSC colony formation. Knockdown of Zfhx1b...

Encephalitis and GABAB receptor antibodies: novel findings in a new case seri...

Höftberger(Romana),Titulaer(Maarten J),Sab... Neurology 2013-12-11

...SOX1), and 2 without tumor had GAD65 and NMDAR antibodies, respectively. GABABR antibodies were not detected in serum of...

Stem cells expanded from the human embryonic hindbrain stably retain regional...

Tailor(Jignesh),Kittappa(Raja),Leto(Ketty)... J Neurosci 2013-10-17

...SOX1 expression, formation of rosette-like structures, and high neurogenic capacity. They generate GABAergic, glutamater...

SOX1 suppresses cell growth and invasion in cervical cancer.

Lin(Ya-Wen),Tsao(Chun-Ming),Yu(Pei-Ning),S... Gynecol Oncol 2013-12-27

...SOX1 and monitored its function by in vitro experiments. To confirm SOX1 function, we manipulated SOX1 using an inducibl...

Frequent concomitant epigenetic silencing of SOX1 and secreted frizzled-relat...

Shih(Yu-Lueng),Hsieh(Chung-Bao),Yan(Ming-D... J Gastroenterol Hepatol 2013-08-26

...SOX1 in HCC.,Promoter methylation of SOX1 was significantly frequent in HCC cell lines and clinical HCCs, cirrhotic live...

Cisplatin-induced downregulation of SOX1 increases drug resistance by activat...

Li(Ning),Li(Xiaobing),Li(Suyun),Zhou(Suzhe... Biochem Biophys Res Commun 2013-11-26

...SOX1 in ovarian cancer cell, suggesting that SOX1 may be involved in cisplatin resistance. Our aim was to test the hypot...

Involvement of crosstalk between Oct4 and Meis1a in neural cell fate decision...

Yamada(Takeyuki),Urano-Tashiro(Yumiko),Tan... PLoS One 2013-09-27

...Sox1 as neural stem cell (NSC)/neural progenitor markers, whereas its down-regulation generated small neurospheres and r...

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