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TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Prote…

Zhang(J),Liu(P),Tao(J),Wang(P),Zhang(Y),Song… Am J Pathol 2019-00-00

...TEAD4 consistently inhibited tumor growth and Yap target gene expression in HB cell lines. Furthermore, TEAD4 mRNA expre...

Systematic screening identifies a TEAD4-S100A13 axis modulating cisplatin sensi…

Li(R),Li(W),He(F),Zhang(M),Luo(H),Tang(H) J Oral Pathol Med 2021-10-00

...TEAD4 could bind to the promoter of ENST00000440685 and increase its transcription. TEAD4 overexpression alleviated the ...

Developmental clock and mechanism of de novo polarization of the mouse embryo.

Zhu(M),Cornwall-Scoones(J),Wang(P),Handford(… Science 2020-00-11

...Tead4) expression in the presence of activated Ras homolog family member A (RhoA) induces precocious polarization as wel...

GTSE1: a novel TEAD4-E2F1 target gene involved in cell protrusions formation in…

Stelitano(D),Peche(LY),Dalla(E),Monte(M),Pia… Oncotarget 2017-00-15

...TEAD4 transcription factor, highlighting a role for the YAP and TAZ coactivators in the transcriptional regulation of GT...

Hippo/TEAD4 signaling pathway as a potential target for the treatment of breast…

Wu(Y),Li(M),Lin(J),Hu(C) Oncol Lett 2021-04-00

...TEAD4, plays an important role in breast cancer. TEADs interact with YAP/TAZ to act as transcription factors. Notably, r...

TEAD4, YAP1 and WWTR1 prevent the premature onset of pluripotency prior to the …

Frum(T),Watts(JL),Ralston(A) Development 2019-00-06

...Tead4 Interestingly, the repression of premature Sox2 expression was sensitive to LATS kinase activity, even though LATS...

IRF2BP2 is a skeletal and cardiac muscle-enriched ischemia-inducible activator …

Teng(AC),Kuraitis(D),Deeke(SA),Ahmadi(A),Dug… FASEB J 2010-12-00

...TEAD4/VGLL4 complex in vivo by coimmunoprecipitation and mammalian 2-hybrid assays. Coexpression of IRF2BP2 with TEAD4/V...

TEAD4 antagonizes cellular senescence by remodeling chromatin accessibility at …

Zhang(D),Zhu(Y),Ju(Y),Zhang(H),Zou(X),She(S)… Cell Mol Life Sci 2023-10-19

...TEAD4, moves away from H3K27ac-labled SAAs to allow for prominent chromatin accessibility reconstruction during senescen...

Pharmacological modulation of RB1 activity mitigates resistance to neoadjuvant …

Yu(Z),Deng(P),Chen(Y),Lin(D),Liu(S),Hong(J),… Proc Natl Acad Sci U S A 2024-02-06

...TEAD4/HDAC1 complex to epigenetically suppress the expression of DNA repair genes. Antagonizing RB1 phosphorylation thro...

YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of e…

Li(Y),Zhu(X),Yang(M),Wang(Y),Li(J),Fang(J),G… Mol Carcinog 2021-00-00

...TEAD4 interaction by verteporfin repressed KIF4A expression. Also, KIF4A knockdown significantly inhibited the cell grow...

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