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PFKP Mediates Breast Cancer Metastasis Through Altered Glycolysis.

Anwar(S),Haq(F),Saeed(M) Cureus 2025-07-00

...ENO1, PGM1, LDHB, and PGK1). Gene set enrichment analysis (GSEA) highlighted its role in glucose metabolism, hypoxia, an...

Tumor-intrinsic ENO1 inhibition promotes antitumor immune response and facili...

Shen(C),Liu(J),Hu(D),Liu(C),Xie(F),Wang(Y) J Exp Clin Cancer Res 2025-07-15

...ENO1 knockdown, which also suppressed carcinogenesis. Single-cell RNA sequencing demonstrated that wild-type (WT) and EN...

In-depth exploration of programmed cell death-related subtypes and developmen...

Zhou(D),Cui(Y),Guo(J),Wu(Z),Li(L),Yin(W),D... Sci Rep 2025-07-10

...ENO1, could be used as a target for LUAD prognosis and immunotherapy. This study aims to comprehensively explore the fun...

A novel protein encoded by circUBE2G1 suppresses glycolysis in gastric cancer...

Lu(L),Guo(G),Guo(J),Li(H),Chen(K),Chen(Y),... Cell Death Discov 2025-07-29

...ENO1 and suppressed its glycolytic activity, thereby reducing glycolysis in GC cells. These findings delineate the funct...

Profiling HIV1-host protein-protein interaction networks in patient-derived e...

Fatima(N),Baig(MS),Rizvi(AH),Arzoo(A),Shar... Virol J 2025-07-28

...ENO1, OGT, TJP1, and TRAF6 exosome-derived host proteins participated in regulation. Notably, CDH5, ENO1, OGT, and TRAF6...

Dimeric PKM2 induces ferroptosis from intestinal ischemia/reperfusion in mice...

Liu(Z),Zhou(Y),Li(M),Xiao(Z),Zhao(Z),Li(Y) Biochim Biophys Acta Mol Ba... 2025-11-00

...ENO1, LDHA, and PDK1 levels. Importantly, HMGB1 knockdown completely counterbalanced the promoting effect of PKM2 overex...

Esculetin inhibits the PI3K/Akt/mTOR pathway and enhances anti-colorectal can...

Ma(J),Zhang(M),Mulati(S),Nabi(X),Zhang(W) Front Pharmacol 2025-00-00

...ENO1 protein and altered its stability. Moreover, silencing ENO1 expression reversed the anti-CRC effect of Esc. This st...

Characterization of lactylation modification subtypes and the promoting role ...

Wu(LH),Yang(L),Wang(XX),Bai(S),Yan(X),Wei(... Front Genet 2025-00-00

...ENO1, PFN2, LCAT, PTGR1, and CCL20, was constructed and validated. Overall survival was markedly reduced in the high LRP...

Prognostic significance and potential association between ALDOA and ENO1 in g...

Wang(X),Lu(Y),Cheng(Z),Yao(Y),Shao(X) J Cancer 2025-00-00

...ENO1 significantly impacts the prognosis of GC patients. Conclusions: ALDOA/ENO1 may play a crucial role in GC, which ma...

Myeloperoxidase-anchored ENO1 mediates neutrophil extracellular trap DNA to e...

Jiang(Y),Gao(S),Li(X),Sun(H),Wu(X),Gu(J),C... J Clin Invest 2025-11-03

...ENO1) on the membrane of CD4+ T cells through its key protein myeloperoxidase (MPO) and subsequently recruited interfero...

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