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Hypereosinophilia of persistent/unknown cause: a bone marrow-based study inte...

Eletrebi(MM),Sanchez-Ramirez(J),Abdalla(A)... Am J Clin Pathol 2026-05-05

...PDGFRA in 2 cases), myeloid NGS detected mutations in 47% (7/15) of tested patients with HEPU, involving genes such as T...

Therapeutic manipulation and spatial quantification of the tumor microenviron...

Mulholland-Illingworth(EJ),Moore(JW),Lin(M... iScience 2026-04-17

...PDGFRA+ and ACTA2+ expression, enabling robust spatial identification using single immunohistochemical markers. We show ...

Rare internal malignancies in xeroderma pigmentosum: A report of two cases fr...

Rammeh(S),Ben Taher(Y),Ben Rekaya(M),Ben R... Cancer Pathog Ther 2026-07-00

...PDGFRA) NM_006206.6:c.2525A>T (p.Asp842Val) mutations in renal leiomyosarcoma and NRAS proto-oncogene, GTPase (NRAS) NM_...

Clinicogenomic Characteristics and Treatment Outcomes of Patients With Advanc...

Miao(EA),Yeap(B),Daher(S),Lomibao(M),Sun(F... JCO Precis Oncol 2026-03-00

...PDGFRA (16% v 0%; P = .009), KIT (11% v 0%; P = .045), PIK3CA (11% v 0%; P = .045), and MYC (11% v 0%; P = .045) coalter...

Spatial single cell transcriptomic analysis informs tumor developmental hiera...

Kommoss(FKF),Zhang(JYH),Lynch(BJ),Chen(SY)... Nat Commun 2026-03-30

...Pdgfra+ Dpt+Pi16+ fibroblastic progenitor population, corresponding to universal fibroblasts subjacent to transitional e...

The postnatal expression of transcripts and proteins in the corpus callosum, ...

Mayo(F),González-Vinceiro(L),Hiraldo-Gonzá... J Physiol Biochem 2026-03-31

...PDGFRa+). However, the number of mature oligodendrocytes (OLIG2+/CC1+) was reduced in the KO mice, indicating a failure ...

Benralizumab versus placebo for hypereosinophilic syndrome: a randomized, pla...

Ogbogu(PU),Roufosse(F),Akuthota(P),Kuna(P)... Nat Med 2026-06-00

...PDGFRA-negative HES. The primary endpoint was time to first HES flare. In total, 133 patients (median (range) age 51 (14...

Genetic associations of corneal astigmatism in Hong Kong Chinese children.

Shing(E),Kam(KW),Wang(YY),Zhang(Y),Zhang(X... Sci Rep 2026-03-31

...PDGFRA rs17084051 (P = 0.04) and ZC3H11B rs7525202 (P = 0.01) were associated with linear decrease in CA magnitude acros...

Comparison of gene fusion detection algorithms reveals frequently overlooked ...

Tamura(Z),Saito(Y),Kogure(Y),Oshikawa-Kuma... NPJ Precis Oncol 2026-04-04

...PDGFRA), lowly expressed fusions, and IGH fusions (DUX4::IGH and IGH::NSD2). Targeted RNA-seq more sensitively detected ...

Targeted Therapy for Advanced Gastrointestinal Stromal Tumors: Evolution and ...

Wang(XD),Shou(CH),Chen(SC),Hong(YY),Zhu(KK... Drug Des Devel Ther None

...PDGFRA) genes. Surgical resection remains the standard curative treatment for localized GIST; however, ~50% of patients ...

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