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Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in...

Figueiredo(Ana C),Wasmeier(Christina),Tara... J Biol Chem 2008-10-06

...Rab3a, as the non-redundant Rab27a GEF. Similar to Rab27a-deficient ashen melanocytes, Rab3GEP-depleted cells show both ...

Direct interactions between C. elegans RAB-3 and Rim provide a mechanism to t...

Gracheva(Elena O),Hadwiger(Gayla),Nonet(Mi... Neurosci Lett 2008-11-18

...Rab3A, here we asked whether UNC-10-dependent recruitment of synaptic vesicles to the presynaptic density was through an...

A gain-of-function mutant of Munc18-1 stimulates secretory granule recruitmen...

Graham(Margaret E),Handley(Mark T W),Barcl... Biochem J 2008-02-12

...Rab3A, which is increased by the mutation. Expression of Munc18-1 with the E466K mutation increased exocytosis in adrena...

Detection of the interaction between SNAP25 and rabphilin in neuroendocrine P...

Lee(Jiung-De),Chang(Yu-Fen),Kao(Fu-Jen),Ka... Microsc Res Tech 2008-03-17

...Rab3A specific binding protein, in vitro. However, it is still unclear whether SNAP25 and rabphilin interact during exoc...

Structural basis for the exclusive specificity of Slac2-a/melanophilin for th...

Kukimoto-Niino(Mutsuko),Sakamoto(Ayako),Ka... Structure 2008-12-18

...Rab3A mutant that acquires Slac2-a binding ability by transplanting four Rab27-specific residues into Rab3A. These findi...

Regulation of ENaC expression at the cell surface by Rab11.

Karpushev(Alexey V),Levchenko(Vladislav),P... Biochem Biophys Res Commun 2008-12-05

...Rab3a small G proteins with ENaC results in a significant increase in channel activity. In contrast, coexpression of Rab...

Rab3a deletion reduces vesicle docking and transmitter release at the mouse d...

Coleman(W L),Bill(C A),Bykhovskaia(M) Neuroscience 2007-12-14

...rab3a function implies that vesicle docking and action potential-evoked release might be inhibited in rab3a gene-deleted...

Membrane-permeant Rab3A triggers acrosomal exocytosis in living human sperm.

Lopez(Cecilia I),Belmonte(Silvia A),De Bla... FASEB J 2007-12-26

...Rab3A, when fused with an arginine-rich peptide, were able to translocate into sperm. Moreover, membrane-permeant Rab3A ...

Loss of SNAP-25 and rabphilin 3a in sensory-motor cortex in Huntington's dise...

Smith(Ruben),Klein(Pontus),Koc-Schmitz(Yel... J Neurochem 2007-11-07

...rab3a or synaptophysin are unaltered in the same patient samples. SNAP 25 and rabphilin 3a are crucial for neurotransmit...

SNAREing voltage-gated K+ and ATP-sensitive K+ channels: tuning beta-cell exc...

Leung(Yuk M),Kwan(Edwin P),Ng(Betty),Kang(... Endocr Rev 2007-11-27

...rab3a-interacting molecule, and guanyl nucleotide exchange factor II, have also been implicated in direct or indirect re...

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