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TP53 BRCA1 CRISPR single-cell cancer

Niederberger(C),Schweingruber(M E) Mol Gen Genet 1999-04-07

...PDK1) and its rat and Drosophila homologues. The two mutants have the same substitution at amino acid position 159: a gl...

Casamayor(A),Torrance(P D),Kobayashi(T),Th... Curr Biol 1999-04-22

...PDK1). Activated PDK1 then phosphorylates and activates downstream protein kinases, including protein kinase B (PKB)/c-A...

Meier(R),Hemmings(B A) J Recept Signal Transduct R... 1999-06-15

...PDK1 and an as yet identified protein kinase). Prolonged stimulation with growth factors results in nuclear translocatio...

Park(J),Leong(M L),Buse(P),Maiyar(A C),Fir... EMBO J 1999-08-05

...PDK1 with SGK caused a 6-fold activation of SGK activity, whereas kinase-dead PDK1 caused no activation. GST-pulldown as...

Peterson(R T),Schreiber(S L) Curr Biol 1999-11-17

...PDK1 as a kinase that phosphorylates the AGC family of kinases led to a hunt for 'PDK2', a hypothetical regulated kinase...

Bowker-Kinley(M M),Davis(W I),Wu(P),Harris... Biochem J 1998-02-11

Tissue distribution and kinetic parameters for the four isoenzymes of pyruvate dehydrogenase kinase (PDK1, PDK2, PDK3 an...

Wu(P),Sato(J),Zhao(Y),Jaskiewicz(J),Popov(... Biochem J 1998-02-11

...PDK1 and PDK2 protein and the abundance of their messages occurred in response to starvation and diabetes. The observed ...

Alessi(D R),Deak(M),Casamayor(A),Caudwell(... Curr Biol 1998-02-10

...PDK1. IGF1 stimulation of 293 cells did not affect the activity or phosphorylation of PDK1.,PDK1 is likely to mediate th...

Thelen(J J),Muszynski(M G),Miernyk(J A),Ra... J Biol Chem 1998-11-02

...PDK1) and 1602 (PDK2) nucleotides in length, encoding polypeptides with calculated molecular masses of 38,867 and 41,327...

Le Good(J A),Ziegler(W H),Parekh(D B),Ales... Science 1998-10-08

...PDK1. PDK1-dependent phosphorylation of PKCdelta in vitro was stimulated by combined PKC and PDK1 activators. The activa...

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