...COL2A1, ACAN, CHAD, and CNMD. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses revealed en...
...COL2A1⁺ chondrocytes (displaying a reparative hyaline cartilage phenotype) were significantly enriched in ONFH. Immunohi...
...Col2a1). In vitro experiments were performed via pharmacological and genetic SIRT3 inhibition. To protect chondrocytes, ...
...COL2A1, and FN1. Additionally, core genes of the PI3K-Akt signaling pathway, such as AKT1, ITGA2B, and MYB, were also do...
...COL2A1), hypertrophic markers (COL10A1, RUNX2), and matrix production (GAG/DNA, type II collagen ELISA). Functional outc...
...Col2a1-CreERT2/Erk5flox/flox mice, we found that Erk5 deletion in cartilage inhibited the progression of post-traumatic ...
...COL2A1). Gene and protein expressions of TET1, TET2, TET3, and hTERT were analyzed through real-time polymerase chain re...
...COL2A1 expression and enhance chondrocyte stress adaptation under specific post-traumatic and redox conditions. Lactylat...
...COL2A1, and SOX9 expression and reduced IL-1β-induced increases in MMP13, ADAMTS5, COL10A1, RUNX2, and IL-6 immunoreacti...
...COL2A1, while limiting fibrocartilage- and hypertrophy-associated markers. Transcriptomic analysis reveals that this res...
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