Hobert(Elissa M),Schepartz(Alanna) J Am Chem Soc 2012-06-28

...Hck to phosphorylate hDM2, a negative regulator of the p53 tumor suppressor and a poor Hck substrate. Phosphorylation oc...

Gong(Jie),Yan(Jin-chuan),Gu(Hai-yong),Kong(X… Mol Biol Rep 2012-08-13

...Hck isoform could play a specific role, little study focus on the function of p56Hck. To investigated the role of p56Hck...

Guiet(Romain),Vérollet(Christel),Lamsoul(Isa… J Biol Chem 2012-06-19

...Hck, and (iv) is necessary for mesenchymal migration but dispensable for amoeboid migration. These new functions assigne...

Bouchet(Jérôme),Hérate(Cécile),Guenzel(Carol… J Virol 2012-06-18

...Hck. We previously described a single-domain antibody (sdAb) targeting Nef and inhibiting many, but not all, of its biol...

Montero(Juan Carlos),Seoane(Samuel),Ocaña(Al… Clin Cancer Res 2012-02-24

...HCK, FYN, YES, FGR, BLK, LYN, and FRK), and the receptor tyrosine kinases c-KIT, platelet-derived growth factor receptor...

Zhu(Jing W),Doan(Kristin),Park(Jason),Chau(A… Immunity 2012-01-18

...Hck and Fgr versus Lyn, respectively) to positively and negatively regulate GPCR pathways.

Huang(Renhua),Fang(Pete),Kay(Brian K) N Biotechnol 2012-11-13

...Hck, Lck, Lyn, Src and Yes), even though they share 51-81% amino acid identity. The other two bind principally to the Fy...

Liu(Lin),Huang(Na),Chen(Lei),Wang(Xiao-Zhen)… Exp Lung Res 2012-05-03

Hematopoietic cell kinase (Hck), a Src family kinase, has been recently suggested to be implicated in the pathogenesis o...

Chutiwitoonchai(Nopporn),Hiyoshi(Masateru),M… PLoS One 2012-03-26

...Hck, which binds to a PxxP motif in Nef, also reduced viral infectivity. Importantly, 2c inhibited Hck SH3-Nef binding, ...

Smolinska(Maria J),Page(Theresa H),Urbaniak(… J Immunol 2012-01-13

...Hck, has a pre-eminent role in LPS/TLR4-induced TNF and IL-6 production. Hck kinase mediates TLR4-induced transcription ...