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Cartilage inflammation and degeneration is enhanced by pro-inflammatory (M1) ...

Utomo(L),Bastiaansen-Jenniskens(Y M),Verha... Osteoarthritis Cartilage 0000-00-00

...COL2A1 (collagen type II). M(IL-10) upregulated IL1B and Suppressor of cytokine signaling 1 (SOCS1). NO production and G...

MicroRNA-99a regulates early chondrogenic differentiation of rat mesenchymal ...

Zhou(Xiaozhong),Wang(Jing),Sun(Hongtao),Qi... Cell Tissue Res 0000-00-00

...COL2A1 during early chondrogenic differentiation. MiR-99a knockdown promoted early chondrogenic differentiation of rMSCs...

Salubrinal Suppresses IL-17-Induced Upregulation of MMP-13 and Extracellular ...

Yao(Zhixiao),Nie(Lin),Zhao(Yunpeng),Zhang(... Inflammation 0000-00-00

...COL2A1), collagen type I (COL1A1), and aggrecan (ACAN) in nucleus pulpous (NP) tissue. Activation of the NF-kB pathway w...

Functional quantum dot-siRNA nanoplexes to regulate chondrogenic differentiat...

Wu(Yang),Zhou(Bo),Xu(Fuben),Wang(Xiaoyong)... Acta Biomater 0000-00-00

...col2a1 in MSCs and further delayed cartilage repair. Moreover, QD-SMCC has an intrinsic signal for noninvasive imaging o...

Parathyroid hormone 1-34 reduces dexamethasone-induced terminal differentiati...

Chang(Ling-Hua),Wu(Shun-Cheng),Chen(Chung-... Toxicology 0000-00-00

...Col2a1), and aggrecan and reduced synthesis of cartilaginous matrix (Col2a1 and sulfated glycosaminoglycan) synthesis. D...

Chondrogenic commitment of human umbilical cord blood-derived mesenchymal ste...

Gómez-Leduc(Tangni),Hervieu(Magalie),Legen... Sci Rep 0000-00-00

...COL2A1, COL2B, ACAN) and protein (type II collagen) markers. Although growth factors increased the transcription of hype...

mTORC1 Signaling Promotes Limb Bud Cell Growth and Chondrogenesis.

Jiang(Ming),Fu(Xuejie),Yang(Huilin),Long(F... J Cell Biochem 0000-00-00

...Col2a1. Thus, we have identified an important role for mTORC1 signaling in promoting limb mesenchymal cell growth and ch...

Inhibition of microRNA-222 expression accelerates bone healing with enhanceme...

Yoshizuka(Masaaki),Nakasa(Tomoyuki),Kawani... J Orthop Sci 0000-00-00

...COL2A1), aggrican, and SOX9. Bone union at the fracture site was achieved in only the groups treated with the miR-222 in...

Cinacalcet ameliorates aortic calcification in uremic rats via suppression of...

Wu(Min),Tang(Ri-Ning),Liu(Hong),Pan(Ming-M... Acta Pharmacol Sin 0000-00-00

...COL2A1) and chondrocyte proteoglycan in uremic aortas. Moreover, CINA treatment largely abolished the up-regulation of m...

Histone Deacetylase Inhibitor Vorinostat (SAHA) Suppresses IL-1β-Induced Matr...

Makki(Mohammad Shahidul),Haqqi(Tariq M) Am J Pathol 0000-00-00

...COL2A1 and ACAN expression in OA chondrocytes that was down-regulated by IL-1β. Of importance is our finding that IL-6-s...

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