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Flavonoid galetin 3,6-dimethyl ether attenuates guinea pig ileum contraction ...

Vasconcelos(Luiz H C),Correia(Ana C de C),... Eur J Pharmacol 2016-10-05

...CaV1, thus leading to a reduction in cytosolic Ca(2+) levels.

Absence of caveolin-1 leads to delayed development of chronic lymphocytic leu...

Shukla(Ashima),Cutucache(Christine E),Sutt... Exp Hematol 2016-04-19

...Cav1(-/+) and Eμ-TCL1-Cav1(-/-) mice as compared with Eμ-TCL1 mice. In addition, there was a significant increase in sur...

A Genetic Variant in TGFBR3-CDC7 Is Associated with Visual Field Progression ...

Trikha(Sameer),Saffari(Ehsan),Nongpiur(Mon... Ophthalmology 2016-03-17

...CAV1-CAV2, CDKN2B-AS1, SIX1-SIX6, an intergenic region on chromosome 8q22, ABCA1, GAS7, AFAP1, GMDS, PMM2, and TGFBR3-CD...

Systematically identify key genes in inflammatory and non-inflammatory breast...

Chai(Fan),Liang(Yan),Zhang(Fan),Wang(Mingh... Gene 2016-03-17

...CAV1, COL5A1 and MMP2 to be the key genes for breast cancer. Interestingly, PDGFRβ was found to be the hub gene in both ...

Molecular Characterization of Caveolin-induced Membrane Curvature.

Ariotti(Nicholas),Rae(James),Leneva(Nataly... J Biol Chem 2016-01-15

The generation of caveolae involves insertion of the cholesterol-binding integral membrane protein caveolin-1 (Cav1) int...

A caveolin-dependent and PI3K/AKT-independent role of PTEN in β-catenin trans...

Conde-Perez(Alejandro),Gros(Gwendoline),Lo... Nat Commun 2016-04-26

...CAV1 mRNA in melanoma cells. These data reveal a mechanism by which loss of PTEN increases CAV1-mediated dissociation of...

Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorat...

Zhang(Ping-Xia),Cheng(Jijun),Zou(Siying),D... Nat Commun 2016-02-01

...CAV1 with subsequent uncontrolled TLR4 signalling. Here we show that reduced CAV1 and, consequently, increased TLR4 sign...

Novel nonsense mutation in the PTRF gene underlies congenital generalized lip...

Jelani(Musharraf),Ahmed(Saleem),Almramhi(M... Eur J Med Genet 2016-01-28

...CAV1 at 7q31.1, and PTRF at 17q21.2. In this study, we performed genome-wide homozygosity mapping of two affected and on...

The genetics of POAG in black South Africans: a candidate gene association st...

Williams(Susan E I),Carmichael(Trevor R),A... Sci Rep 2016-02-04

...CAV1/CAV2, CYP1B1, COL1A2, COL5A1, CDKN2B/CDKN2BAS-1, SIX1/SIX6 or the chromosome 2p16 regions and there were no associa...

The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth i...

Kobayashi(Kazuyoshi),Sakurai(Kouhei),Hiram... Sci Rep 2016-02-02

...CAV1 and CAV2 (miR-199a targets), all of which function as plasma membrane sensors and can co-localize in caveolae, are ...

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