Meuwissen(Pieter J),Stolp(Bettina),Iannucci(… Retrovirology 2012-12-14

...Hck.,Based on these findings, we propose that this highly conserved three amino acid VGF motif together with the acidic ...

Pene-Dumitrescu(Teodora),Shu(Sherry T),Wales… BMC Chem Biol 2012-10-02

...Hck SH3 domain to enhance interaction of the kinase with Nef. This modification stabilized Nef:Hck interaction in soluti...

Narute(Purushottam S),Smithgall(Thomas E) PLoS One 2012-07-23

...Hck and Lyn as well as c-Src to a lesser extent, demonstrating for the first time that Src-family kinase activation is a...

van Bodegom(Diederik),Zhong(Jun),Kopp(Nadja)… Blood 2012-12-18

...Hck, Syk, MAPK8, MAPK9, and MAPK10. We now demonstrate that cells dependent on CRLF2/mutant JAK2 have reduced phosphoryl...

Zhu(Jing W),Doan(Kristin),Park(Jason),Chau(A… Immunity 2012-01-18

...Hck and Fgr versus Lyn, respectively) to positively and negatively regulate GPCR pathways.

Liu(Lin),Huang(Na),Chen(Lei),Wang(Xiao-Zhen)… Exp Lung Res 2012-05-03

Hematopoietic cell kinase (Hck), a Src family kinase, has been recently suggested to be implicated in the pathogenesis o...

Chutiwitoonchai(Nopporn),Hiyoshi(Masateru),M… PLoS One 2012-03-26

...Hck, which binds to a PxxP motif in Nef, also reduced viral infectivity. Importantly, 2c inhibited Hck SH3-Nef binding, ...

Smolinska(Maria J),Page(Theresa H),Urbaniak(… J Immunol 2012-01-13

...Hck, has a pre-eminent role in LPS/TLR4-induced TNF and IL-6 production. Hck kinase mediates TLR4-induced transcription ...

Zou(Dandan),Yang(Xianwen),Tan(Yun),Wang(Ping… Leuk Res 2012-02-16

...HCK) in acute promyelocytic leukemia (APL) and the underlying molecular mechanisms. First, the level of HCK in APL blast...

Huang(Renhua),Fang(Pete),Kay(Brian K) N Biotechnol 2012-11-13

...Hck, Lck, Lyn, Src and Yes), even though they share 51-81% amino acid identity. The other two bind principally to the Fy...