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Deciphering the metabolic landscape of MYCN non-amplified neuroblastoma throu...

Li(L),Lin(Y),Liu(S),Wang(Z) FEBS J 2026-06-18

...MYCN-amplified (MYCN-A) group, the MYCN-NA group exhibited higher proportions of T cells, monocytes, and neurons, while ...

Clinical responses to trastuzumab deruxtecan in molecularly defined ependymom...

Gonzalez Castro(LN),Wu(YC),Lin(JR),Santiag... NPJ Precis Oncol 2026-06-20

...MYCN-amplified spinal tumor with intracranial dissemination and a supratentorial ZFTA-RELA-fused tumor with multiple rec...

Arsenic trioxide triggers ferroptosis in neuroblastoma via USF1/GPX4 axis.

Ma(Y),Liu(X),Su(M),Wang(Z),Peng(X),Wang(W)... Bioorg Chem 2026-09-15

...MYCN-amplified SK-N-BE(2) cells. This study demonstrates that ATO triggers ferroptosis in NB cells via the USF1/GPX4 axi...

A MYCN-GAL-SREBP1 Lipogenic Axis Drives Proliferation in Silent Corticotroph ...

Han(C),Wu(J),Xie(J),Li(J),He(Z),Zhang(B),D... Neuro Oncol 2026-06-23

...MYCN directly upregulates GAL; however, MYCN downregulation in SCAs suppresses GAL expression, thereby enabling SREBP1-d...

YTHDF1-modified neural stem cells confer neuroprotection and promote function...

Zhang(X),Wang(J),Lu(Y),Xu(F),Cheng(X),Qin(... Brain Res Bull 2026-09-00

...MYCN, and exert neuroprotective effects through the PI3K/AKT signaling pathway.

Anti-Tumor Activity of Cdk2/9 Inhibitor Fadraciclib in an In Vivo Model of Te...

Poon(E),Liang(T),Gao(Q),Barone(G),Martins ... Mol Cancer Ther 2026-06-24

...MYCN genetically-engineered mouse model, concomitant with the acquisition of resistance to temozolomide, a standard chem...

The Genomic Landscape of MYC, MYCL, and MYCN Amplified Solid Tumors.

Repetto(M),Richards(AL),Chen(MF),Selenica(... Clin Cancer Res 2026-06-24

...MYCN. While MYCN and MYCL amplifications were predominantly focal (<10Mb, 79% and 93% respectively), MYC amplifications ...

Impact of salvage treatment for recurrent medulloblastoma in previously irrad...

Chun(SJ),Kim(N),Lim(DH),Kim(JY),Wee(CW),Yo... Clin Transl Radiat Oncol 2026-07-00

...MYCN non-amplification, chemotherapy, and LCT were associated with improved PFS. In multivariate analysis, both chemothe...

Intramedullary Spinal Cord Tumors in Pediatric Patients.

Lehner(KR),Xia(Y),Groves(ML) Neurosurg Clin N Am 2026-07-00

...MYCN amplification-refining diagnosis and prognosis. Children often present with progressive pain, motor deficits, or sc...

When the cure becomes the curse: Radiation-induced glioma of the pons in chil...

Ul Ain(R),Gorsi(HS),Habre(C),Bartoli(A),Tr... Neurooncol Pract 2026-08-00

...MYCN, PDGFRA, and MDM2 amplification and a novel fusion (RBD7-FLI1), while the other case had an inconclusive histopatho...

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