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Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis a...

Yan(Jingliang),Li(Fang),Ingram(David A),Qu... Mol Cell Biol 2008-09-29

...rap1a(-/-) mice, and aortic rings derived from rap1a(-/-) mice failed to sprout primitive tubes in response to FGF2, whe...

Integrin activation.

Banno(Asoka),Ginsberg(Mark H) Biochem Soc Trans 2008-09-05

...Rap1A(G12V) bypassed the requirement for PKCalpha. Overexpression of a Rap effector, RIAM (Rap1-GTP-interacting adaptor ...

Two conformational states of Ras GTPase exhibit differential GTP-binding kine...

Liao(Jingling),Shima(Fumi),Araki(Mitsugu),... Biochem Biophys Res Commun 2008-04-22

...Rap1A, Rap2A and RalA, and find that they exhibit distinctive state 2/state 1 populations with the ratios ranging from 0...

Enhanced cortico-amygdala efficacy and suppressed fear in absence of Rap1.

Pan(Bing-Xing),Vautier(Francois),Ito(Watar... J Neurosci 2008-04-08

...rap1a and rap1b genes impaired synaptic plasticity and increased basal synaptic transmission in the cortical but not tha...

Rap1a null mice have altered myeloid cell functions suggesting distinct roles...

Li(Yu),Yan(Jingliang),De(Pradip),Chang(Hua... J Immunol 2008-03-04

...Rap1a gene. Although loss of Rap1a expression did not initially affect mouse size or viability, upon backcross into C57B...

Visualizing mineral binding and uptake of bisphosphonate by osteoclasts and n...

Coxon(Fraser P),Thompson(Keith),Roelofs(An... Bone 2008-06-30

...Rap1A accumulated to the same extent whether osteoclasts were cultured on RIS-coated dentine or with RIS in solution. By...

A critical role of Rap1b in B-cell trafficking and marginal zone B-cell devel...

Chen(Yuhong),Yu(Mei),Podd(Andrew),Wen(Renr... Blood 2008-07-16

...Rap1a and Rap1b. Although Rap1 has been suggested to have an important role in a variety of cellular processes, no direc...

Cell signaling and transcription factor genes expressed during whole body reg...

Rinkevich(Yuval),Rinkevich(Baruch),Reshef(... BMC Dev Biol 2008-12-09

...Rap1A, Bl-Rab-33), the protein kinase family (Bl-Mnk), Bl-Cnot, Bl-Slit and Bl-Bax inhibitor, revealed systemic and site...

Rap1 activation plays a regulatory role in pancreatic amylase secretion.

Sabbatini(Maria E),Chen(Xuequn),Ernst(Step... J Biol Chem 2008-10-03

...Rap1A/B and the two Rap1 guanine nucleotide exchange factors, Epac1 and CalDAG-GEF III, were identified in mouse pancrea...

Rap1b regulates B cell development, homing, and T cell-dependent humoral immu...

Chu(Haiyan),Awasthi(Aradhana),White(Gilber... J Immunol 2008-09-15

...Rap1a and Rap1b. Although Rap1 has been extensively studied, its isoform-specific functions in B cells have not been elu...

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