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Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric …

Bum-Erdene(K),Zhou(D),Gonzalez-Gutierrez(G),… Cell Chem Biol 2019-00-21

...TEAD4 via a large flat interface, making the development of small-molecule orthosteric inhibitors highly challenging. He...

VGLL1 phosphorylation and activation promotes gastric cancer malignancy via TGF…

Im(JY),Kim(DM),Park(H),Kang(MJ),Kim(DY),Chan… Biochim Biophys Acta Mol Cell… 2021-00-00

We previously reported that vestigial-like 1 (VGLL1), a cofactor of transcriptional enhanced associate domain 4 (TEAD4),...

VGLL4 with low YAP expression is associated with favorable prognosis in colorec…

Kim(JY),Kim(EK),Lee(WM),Hong(YO),Lee(H) APMIS 2020-10-00

...TEAD4 and assessed their correlations with clinicopathologic factors and prognostic effects in 295 colorectal cancers. V...

The YAP1/TAZ-TEAD transcriptional network regulates gene expression at neuromus…

Gessler(L),Huraskin(D),Jian(Y),Eiber(N),Hu(Z… Nucleic Acids Res 2024-01-25

...TEAD4 signaling, particularly through TAZ-TEAD4, in regulating synaptic gene expression and acetylcholine receptor clust...

The YAP-TEAD4 complex promotes tumor lymphangiogenesis by transcriptionally upr…

Song(J),Dang(X),Shen(X),Liu(Y),Gu(J),Peng(X)… J Biol Chem 2023-00-00

...TEAD4 is associated with lymph node metastasis and high lymphatic vessel density in patients with CRC. YAP/TAZ-TEAD4 com...

Genetic variants in Hippo pathway genes YAP1, TEAD1 and TEAD4 are associated wi…

Yuan(H),Liu(H),Liu(Z),Zhu(D),Amos(CI),Fang(S… Int J Cancer 2015-08-01

...TEAD4) from the dataset of our previously published CM genome-wide association study and comprehensively analyzed their ...

Long noncoding RNA LINC01106 promotes lung adenocarcinoma progression via upreg…

Sun(G),Zheng(Y),Cai(J),Gao(J),Dong(L),Zhang(… Oncol Res 2025-00-00

...TEAD4). In turn, TEAD4 served as a transcription factor that bound to the LINC01106 promoter and regulated its expressio...

Lysyl oxidase: A colorectal cancer biomarker of lung and hepatic metastasis.

Liu(Y),Wang(G),Liang(Z),Mei(Z),Wu(T),Cui(A),… Thorac Cancer 2018-00-00

...TEAD4 was explored by YAP or TEAD4 short hairpin RNA interference in a LoVo cell line. LOX messenger RNA expression was ...

A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of…

Li(L),Ugalde(AP),Scheele(CLGJ),Dieter(SM),Na… Genome Biol 2021-00-29

...TEAD4-DNA-binding protein and stimulates cancer aggressiveness. Although thousands of YAP/TEAD4 binding-sites are annota...

TFAP2C exacerbates psoriasis-like inflammation by promoting Th17 and Th1 cells …

Zhang(H),Ren(C),Liu(Q),Wang(Q),Wang(D) Allergol Immunopathol (Madr) 2023-00-00

...TEAD4) genes expression was evaluated by reverse transcription-quantitative polymerase chain reaction. Western blot anal...

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