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Involvement of receptor tyrosine kinase Tyro3 in amyloidogenic APP processing...

Zheng(Yan),Wang(Qi),Xiao(Bing),Lu(Qingjun)... PLoS One 2012-11-08

...Tyro3 were inhibited by its natural ligand, Gas6, in a concentration-dependent manner. In order to confirm the role of T...

Polymorphisms in the receptor tyrosine kinase MERTK gene are associated with ...

Ma(Gerry Z M),Stankovich(Jim),,Kilpatrick(... PLoS One 2012-04-02

...TYRO3, AXL and MERTK) have been implicated as important players during demyelination in both animal models of MS and in ...

Increased plasma levels of the soluble Mer tyrosine kinase receptor in system...

Wu(Jun),Ekman(Carl),Jönsen(Andreas),Sturfe... Arthritis Res Ther 2012-02-27

...Tyro3 (sTyro3) were increased in systemic lupus erythematosis (SLE), rheumatoid arthritis (RA), or critical limb ischemi...

Retinal self-antigen induces a predominantly Th1 effector response in Axl and...

Ye(Fei),Han(Lixia),Lu(Qingjun),Dong(Wanwei... J Immunol 2011-11-15

...Tyro3, Axl, and Mertk) plays an important role in the negative regulation of response of dendritic cells (DCs) and macro...

Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in th...

Weinger(Jason G),Brosnan(Celia F),Loudig(O... J Neuroinflammation 2011-10-03

...Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-...

Gas6 increases myelination by oligodendrocytes and its deficiency delays reco...

Binder(Michele D),Xiao(Junhua),Kemper(Denn... PLoS One 2011-07-05

...Tyro3, Axl and Mertk), as potentially important in regulating both the oligodendrocyte and immune responses. We have pre...

Phosphoproteomic screen identifies potential therapeutic targets in melanoma.

Tworkoski(Kathryn),Singhal(Garima),Szpakow... Mol Cancer Res 2011-10-21

...TYRO3, AXL, MERTK, EPHB2, MET, IGF1R, EGFR, KIT, HER3, and HER4. Statistical analysis of receptor tyrosine kinase activa...

Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis.

Caberoy(Nora B),Zhou(Yixiong),Li(Wei) EMBO J 2011-01-12

...Tyro3, Axl and MerTK of the TAM receptor tyrosine kinase subfamily, whereas tubby binds only to MerTK. Excessive soluble...

Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and...

Cosemans(J M E M),Van Kruchten(R),Olieslag... J Thromb Haemost 2011-03-07

...Tyro3, Axl and Mer (TAM) plays an important role in arterial thrombus formation. However, a role for Gas6 in human plate...

Rethinking the red wolf disease: does Protein S suppress systemic lupus eryth...

Silverman(Gregg J) Arthritis Res Ther 2011-03-31

...Tyro3, Axl and MerTK) family of receptor tyrosine kinases may lead to a better understanding of the fundamental control ...

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