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Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: po…

Montero(Juan Carlos),Seoane(Samuel),Ocaña(Al… Clin Cancer Res 2012-02-24

...HCK, FYN, YES, FGR, BLK, LYN, and FRK), and the receptor tyrosine kinases c-KIT, platelet-derived growth factor receptor...

HIV-1 Nef perturbs the function, structure, and signaling of the Golgi through …

Hiyoshi(Masateru),Takahashi-Makise(Naoko),Yo… J Cell Physiol 2012-04-25

...Hck isoforms and their mutants and Golgi-targeting Hck mutants, we confirmed that Hck activation at the Golgi causes the...

Deregulation of tyrosine kinases in a rat macrophage tumor - ectopic expression…

Sridhar(T),Rema(V),Swarup(G),Khar(A) Int J Oncol 2012-10-02

...hck, a gene expressed predominantly in myeloid cells are markedly reduced in AK-5. The genomic organization of lck is un...

Low and high molecular weight cytokeratins in invasive breast carcinoma.

Takei(H),Iino(Y),Horiguchi(J),Maemura(M),Oya… Oncol Rep 2012-10-02

...HCK-positive tumors and those of patients with HCK-negative tumors. LCK-positive IBC can be well differentiated and HCK-...

Rewiring kinase specificity with a synthetic adaptor protein.

Hobert(Elissa M),Schepartz(Alanna) J Am Chem Soc 2012-06-28

...Hck to phosphorylate hDM2, a negative regulator of the p53 tumor suppressor and a poor Hck substrate. Phosphorylation oc...

Expressing murine p56Hck(ca) promotes HeLa cells' motility and invasion via tri…

Gong(Jie),Yan(Jin-chuan),Gu(Hai-yong),Kong(X… Mol Biol Rep 2012-08-13

...Hck isoform could play a specific role, little study focus on the function of p56Hck. To investigated the role of p56Hck...

Butyrate reduced lipopolysaccharide-mediated macrophage migration by suppressio…

Maa(Ming-Chei),Chang(Miao Ying),Hsieh(Ming-Y… J Nutr Biochem 2011-02-28

...Hck) whose expression was almost unaltered in the presence or absence of butyrate in LPS-treated macrophages, LPS-mediat...

Effect of mixed crowding on refolding of human muscle creatine kinase.

Lin(Zhi-Min),Li(Sen) Protein Pept Lett 2011-03-10

...HCK) were studied by enzyme activity assay and aggregation measurements. The results showed that sucrose and dextran hav...

Crystal structure of the Src family kinase Hck SH3-SH2 linker regulatory region…

Alvarado(John J),Betts(Laurie),Moroco(Jamie … J Biol Chem 2011-02-09

...Hck protein. Our results also provide fresh structural insight into the facile induction of Hck activity by HIV-1 Nef an...

Novel fluorescent dyes based on oligopropylamines for the in vivo staining of e…

Annenkov(V V),Danilovtseva(E N),Zelinskiy(S … Anal Biochem 2011-01-18

...HCK-123. NBD-N3 also efficiently stained other subcellular vesicles of eukaryotic unicellular algae. NBD-N2 stained only...

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