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Pro-Tumorigenic Signaling Between Small Extracellular Vesicles of Cancer Cell...

Attem(J),Jogula(RMR),Kaliki(S),Vemuganti(G... Int J Mol Sci 2026-03-13

...MYCN genes within developing retinal cells. Chemoresistance and metastasis are major challenges for treatment, with the ...

Acetylated Nanoformulation of N-(4-Hydroxyphenyl)-4-Oxoretinamide Inhibits EZ...

Mrunalini(B),Dev(A),Karmakar(S) Small 2026-05-00

...MYCN. The epigenetic regulator EZH2, a histone methyltransferase of the PRC2 complex, is overexpressed in NB and linked ...

Molecular and clinical features of a Japanese medulloblastoma cohort: Subgrou...

Go(K),Katsuma(A),Yoshioka(E),Shofuda(T),Fu... Brain Pathol 2026-09-00

...MYCN amplification and TP53 mutations were independent adverse markers in SHH MB. Group 3 showed the worst survival, wit...

Engineered Peptide Coassembly Enables Precision Delivery of As(III)-Peptide C...

Zeng(Y),Zhang(W),Chen(J),Luo(S),Wu(Y),Hu(C... ACS Nano 2026-03-24

High-risk neuroblastoma (HR-NB) remains a devastating pediatric malignancy characterized by MYCN amplification-induced a...

Factors Influencing Immunotherapy Response in Neuroblastoma: From Tumor Micro...

Du(X),Dong(R),Dong(K) Cells 2026-02-28

...MYCN amplification-associated downregulation of MHC-I, and heterogeneity of GD2 antigen expression; (3) host factors, su...

Gene Amplification in Rhabdomyosarcoma: Lessons from a Rare Cancer.

Barr(FG) Int J Mol Sci 2026-03-06

...MYCN). In contrast, amplification of the 12q13-q14 chromosomal region involves a gene-rich region in which there are at ...

Developmental reprogramming underlies chemotherapy resistance in favorable-hi...

Fleming(AM),Jablonowski(CM),Jin(H),Zhang(S... Cell Rep 2026-03-24

...MYCN copy gain/upregulation and chromatin remodeling. ABCB1 expression correlates with interchromosomal enhancer interac...

LMO1 expression in neuroblastoma cells reprograms tumor-associated macrophage...

Tan(KE),Her(ZP),Zhang(C),Yeo(KS),Weiskitte... iScience 2026-03-20

...MYCN oncogene to enhance NB tumorigenesis and metastasis. To better understand this synergy, we performed single-cell RN...

A Human Stem Cell Model of Neuroblastoma Identifies Four Chromosome 17q Genes...

Fang(W),Cheng(B),Pastor(S),Zobel(MJ),Porra... Cancer Lett 2026-08-26

...MYCN/17q+ tumors compared to MYCN alone. Of these six genes, knockdown of BIRC5, CDC6, IGF2BP1, or TK1 in MYCN/17q+ cell...

ATRX large deletions and truncating mutations are associated with primary ind...

Sun(J),Qian(B),Lu(L),Zhou(J) Front Oncol None

...MYCN amplification status. Large ATRX deletions and truncating mutations identify an ultrahigh-risk molecular subtype of...

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