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Survival-apoptosis associated signaling in GNE myopathy-cultured myoblasts.

Harazi(Avi),Chaouat(Malka),Shlomai(Zippora... J Recept Signal Transduct R... 2016-08-16

...PDK1 and a trend of relative differences in the expression and activation of the examined signaling molecules with varia...

Spinal Myxopapillary Ependymomas Demonstrate a Warburg Phenotype.

Mack(Stephen C),Agnihotri(Sameer),Bertrand... Clin Cancer Res 2016-06-14

...PDK1, and phosphorylation of PDHE1A. Functional assays were performed on MPE lysates, which demonstrated decreased PKM a...

PDK1 induces JunB, EMT, cell migration and invasion in human gallbladder cancer.

Lian(Shixian),Shao(Yebo),Liu(Houbao),He(Ju... Oncotarget 2016-08-04

...PDK1) is upregulated in cancer. Here we showed that PDK1 stimulated cell proliferation, invasion and metastasis in gallb...

[Novel mechanism for invasion and metastasis involving metabolic enzymes in i...

Konno(Masamitsu),Hamabe(Atsushi),Doki(Yuic... Rinsho Ketsueki 2016-02-01

...PDK1 and LDHA. To investigate the significance of PKM2 in epithelial-mesenchymal transition (EMT), a biological process ...

Association of Factor V Secretion with Protein Kinase B Signaling in Platelet...

Norris(J W),Pombo(M),Shirley(E),Blevins(G)... J Vet Intern Med 2016-06-06

...PDK1) signaling were normal. SH2-containing inositol-5'-phosphatase 1 (SHIP1) did not localize to the cytoskeleton of af...

PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breas...

Dupuy(Fanny),Tabariès(Sébastien),Andrzejew... Cell Metab 2016-07-29

...PDK1). Silencing HIF-1α reversed the glycolytic phenotype of liver-metastatic cells, while PDK1 was specifically require...

A Genome-Wide mRNA Screen and Functional Analysis Reveal FOXO3 as a Candidate...

Chen(Biao),Xu(Jiguo),He(Xiaomei),Xu(Haipin... PLoS One 2016-05-31

...PDK1 and PDK4. Moreover, 18 SNPs were identified in FOXO3. G66716193A was significantly (P < 0.05) associated with growt...

PDK1/Akt/PDE4D axis identified as a target for asthma remedy synergistic with...

Fang(R),Cui(Q),Sun(J),Duan(X),Ma(X),Wang(W... Allergy 2016-11-09

...PDK1 with an ideal binding free energy -25.45 kcal/mol and inhibited PDK1 kinase activity without changing its protein l...

Different Mechanisms of Regulation of the Warburg Effect in Lymphoblastoid an...

Mushtaq(Muhammad),Darekar(Suhas),Klein(Geo... PLoS One 2016-05-12

...PDK1 genes, respectively, in the Burkitt lymphoma (BL) cell line P493-6, carrying an inducible MYC gene repression syste...

Expression profile of critical genes involved in FGF signaling pathway in the...

Huang(Feng),Hu(Xiaoxiao),Fang(Chunni),Liu(... Histochem Cell Biol 2016-08-17

...PDK1 expression reveal spatial and temporal patterns of FGF signaling during morphogenesis and organogenesis of human to...

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