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The influence of P-glycoprotein expression and its inhibitors on the distributi…

Patel(Krupa J),Tannock(Ian F) BMC Cancer 2010-01-13

...PgP overexpressing tumors, and treatment of PgP overexpressing tumors with PgP inhibitors led to steeper gradients and g...

Purification of functional human P-glycoprotein expressed in Saccharomyces cere…

Mao(Q),Scarborough(G A) Biochim Biophys Acta 1997-08-19

...Pgp, suggesting that the purified Pgp from yeast is highly functional. The Pgp expressed in yeast has the same electroph...

The expression of P-glycoprotein in AML cells with FLT3 internal tandem duplica…

Hunter(Hannah M),Pallis(Monica),Seedhouse(Cl… Br J Haematol 2004-11-24

...pgp. The concurrent incubation with the pgp inhibitor PSC833 resulted in an enhanced cell kill in 4/5 ITD pgp-positive s...

Fusion of cellobiose phosphorylase and potato alpha-glucan phosphorylase facili…

Liu(X),Hou(H),Li(Y),Yang(S),Lin(H),Chen(H) Prep Biochem Biotechnol 2022-00-00

...PGP) from Solanum tuberosum were the two key enzymes responsible for the whole conversion rate. In this work CBP and PGP...

Prognostic value of P-glycoprotein and leukocyte differentiation antigens in ch…

Stavrovskaya(A),Turkina(A),Sedyakhina(N),Str… Leuk Lymphoma 1998-07-22

...Pgp) mediated multidrug resistance is often the cause of therapy failure in some tumors. Pgp expression was shown to hav...

A novel areneisonitrile Tc complex inhibits the transport activity of MDR P-gly…

Rao(V V),Herman(L W),Kronauge(J F),Piwnica-W… Nucl Med Biol 1998-07-30

...Pgp efflux transport activity. From a series of novel substituted areneisonitrile analogues of Tc-sestamibi, a known Pgp...

A novel peptide CXCR ligand derived from extracellular matrix degradation durin…

Weathington(Nathaniel M),van Houwelingen(Ann… Nat Med 2006-05-17

...PGP was generated in mouse lung after exposure to lipopolysaccharide, and in vivo and in vitro blockade of PGP with mono...

P-glycoprotein expression on acute myeloid leukaemia blast cells at diagnosis p…

Wood(P),Burgess(R),MacGregor(A),Yin(J A) Br J Haematol 1995-01-13

...Pgp positive group than in the Pgp negative group (60% v 92%; P = 0.02). The overall survival for Pgp-positive patients ...

P-glycoprotein dysfunction contributes to hepatic steatosis and obesity in mice.

Foucaud-Vignault(Magali),Soayfane(Zeina),Mén… PLoS One 2012-03-01

...Pgp, we have investigated the possible involvement of Pgp in lipid homeostasis in vivo. In a long term study, we have fo...

Reversal of multidrug resistance: lessons from clinical oncology.

Bates(Susan F),Chen(Clara),Robey(Robert),Kan… Novartis Found Symp 2002-12-04

...Pgp; and the inability to conclusively prove that Pgp modulation was occurring in tumours in patients. New approaches ar...

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