Murayama(Takashi),Kawasoe(Yasuomi),Yamashi... Anticancer Res 2008-09-16

...Rap1A and Ras and phosphorylation of Erk1 and 2 were examined by Western blot analysis. Genomic DNA fragmentation and TU...

Béraud-Dufour(Sophie),Gautier(Romain),Albi... FEBS J 2008-01-17

...Rap1A, preferentially its GTP-bound form. We show that, like other FERM proteins, Krit1 adopts two conformations: a clos...

Tew(Gaik Wei),Lorimer(Ellen L),Berg(Tracy ... J Biol Chem 2008-03-20

...Rap1A, Rap1B, RhoC, and Rac1. SmgGDS is an unusual guanine nucleotide exchange factor that activates many of these small...

Holmes(Simon),Smith(Susan),Borthwick(Lee),... Biochem Biophys Res Commun 2008-01-10

...Rap1A in contrast to cells treated with alendronate. Importantly, CMT3 induced a rapid loss of mitochondrial stability i...

Bigler(Dora),Gioeli(Daniel),Conaway(Mark R... Prostate 2007-11-06

...Rap1a/b and Rap2a/b. Here we ask if Rap proteins play a role in determining androgen sensitivity of human prostate cance...

Merrell(Melinda A),Wakchoure(Savita),Lehen... Eur J Pharmacol 2007-11-30

...Rap1A or Rac1 activation. Geranylgeranyl pyrophosphate, an end-product of the mevalonate pathway, reversed the accumulat...

Koizumi(Masayuki),Nakaseko(Chiaki),Ohwada(... Eur J Haematol 2007-11-09

...Rap1A, were unprenylated in the ZOL-treated MM cells. Geranylgeraniol reduced the above-mentioned ZOL-induced effects. T...

Goldfinger(Lawrence E),Ptak(Celeste),Jeffe... J Proteome Res 2007-07-24

We used a TAP-tag approach to identify candidate binding proteins for the related Ras family GTPases: H-Ras, R-Ras, and ...

Ishikawa(Chie),Matsuda(Takehiro),Okudaira(... Br J Haematol 2007-03-29

...Rap1A protein. These results demonstrated that incadronate-induced growth suppression occurs by interfering with the mev...

Roelofs(Anke J),Edwards(Claire M),Russell(... J Pharmacol Exp Ther 2007-08-30

...Rap1A by lovastatin was enhanced in the presence of apomine. Furthermore, synergy was completely prevented by mevalonate...