...PDGFRA signaling. Alternative therapeutic approaches also include exploring novel inhibitors of the KIT/PDGFRA receptors...
...PDGFRA, which result in constitutive activation of the receptor tyrosine kinase pathway, are important in GIST tumorigen...
...PDGFRA) exons 12 and 18 was performed in cases with a relatively high proportion of either KIT- or DOG1-positive cells. ...
...PDGFRA, PTEN, CDKN2A, RB1, and TP53. Predictive model accuracies (on LOOCV) varied by driver gene of interest. Highest a...
...PDGFRA.,Given the homogeneity of this series and the sensitivity of NGS in this low-cellularity tumor, we demonstrated f...
...PDGFRA mutations and 10 cases of KIT/PDGFRA wild GISTs.,GISTs of 11 men and 13 women with a mean age 54 years(range 29-7...
...PDGFRA, PDGFRB, CD31, CD44, bcl-xL, KIT, p21, CXCR4, PTEN, (CSF)-1R, RET, and FLT-3) can predictive the different effect...
...PDGFRA mutations. Ten micro-GISTs (77%) were located in the stomach, two (15%) in the duodenum, and one (8%) in the rect...
...PDGFRA, PDGFRB or FGFR1. Many of these patients are responsive to tyrosine kinase inhibitor (TKI) therapy. In this , we...
...PDGFRA (4q12) and PDGFRB (5q32-33). The similar changes in the karyotype were also found in the lymph node cells. The un...
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