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Molecular Advances in Juvenile Myelomonocytic Leukemia and Associated RASopathy.

Monika(F),Abu Mehsen(S),Zhang(L) Cancers (Basel) 2026-05-20

...KRAS, NF1, or CBL-establishing JMML as the prototypical malignant manifestation of RASopathy biology. The fifth edition ...

Diabetes-Driven Post-Translational Remodeling in Pancreatic Ductal Adenocarci...

Kavyashree(S),Harithpriya(K),Ganesan(K),Ra... Cancers (Basel) 2026-05-20

...KRAS-MAPK and PI3K-AKT. We introduce the concept of PTM remodeling, wherein transient metabolic perturbations become per...

Prognostic Significance of Cdc42 Expression in Colorectal Cancer and Its Conc...

Aktepe(OH),Butun(O),Kurtulan(O),Karaoglu(A... J Clin Med 2026-05-16

...KRAS) wild-type status (p = 0.001), lymph node metastasis (p = 0.039), and perineural invasion (p = 0.021). Patients wit...

Intratumoral Microbiome of Metastatic Pancreatic Ductal Adenocarcinoma.

Pavlov(V),Snezhkina(A),Pudova(E),Emelyanov... Int J Mol Sci 2026-05-09

...KRAS-mutant and wild-type tumors; however, KRAS-mutant tumors exhibited differential enrichment of K. rosea and L. bugur...

Recent Advances in Pancreatic Cancer and Biliary Tract Cancers: Biology, Biom...

Takrori(E),Abdulmajid(M),Devagudi(D),Sohai... Int J Mol Sci 2026-05-15

...KRAS-directed therapies and rational combination strategies. In BTCs, especially intrahepatic cholangiocarcinoma, compre...

Integrated Genomic Profiling of Pediatric Acute Lymphoblastic Leukemia: Genom...

Stefan-Hodorogea(A),Radu(L),Marcu(A),Serba... Int J Mol Sci 2026-05-18

...KRAS/JAK cluster and an ETV6::RUNX1 cluster characterized by relative mutational exclusivity, with additional associatio...

Pharmacological Mechanisms of Ursolic Acid Derivative Against Prostate Cancer...

Shen(H),Ni(Z),Guo(H),Liu(X),Zhao(Y),He(X),... Pharmaceuticals (Basel) 2026-05-02

...KRAS/RAC1/PIP4K2 axis. Molecular docking results suggested its strong binding affinity and specificity. In vivo studies ...

A Molecular-Protein Fusion Framework for Rapid Virtual Screening: Acceleratin...

Zhou(C),Zhu(Y),Yang(C),Gao(Y),Lu(J),Ming(D... Pharmaceuticals (Basel) 2026-05-12

...KRAS G12D pocket. Conclusions: These findings demonstrate that MPFF-IS can efficiently identify potential KRAS G12D inhi...

[miR-143-3p alleviates neuropathic pain in mice with spared nerve injury by t...

Lin(Y),Yao(J),Chen(Y),Qin(Z) Nan Fang Yi Ke Da Xue Xue B... 2026-05-20

...KRAS was identified as a direct target of miR-143-3p. In SNI mouse models, miR-143-3p significantly inhibited KRAS expre...

Ovarian Mucinous Neoplasms Associated With Mesonephric-like Lesions: An Updat...

Smith(C),Dudley(J),Savage(J),Van de Vijver... Am J Surg Pathol 2026-09-01

...KRAS p.G12A driver mutation in all 3 tumor components (MLA, endometrioid adenocarcinoma, and mucinous tumor), indicating...

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