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P-glycoprotein and multidrug resistance associated protein-1 activity in 132 ac…

Legrand(Ollivier),Zompi(Simona),Perrot(Jean-… Haematologica 2005-03-01

...Pgp and MRP1 to identify subgroups of patients who could benefit from Pgp reversion, and to clarify in different FAB sub...

P-glycoprotein binds to ezrin at amino acid residues 149-242 in the FERM domain…

Brambilla(Daria),Zamboni(Silvia),Federici(Cr… Int J Cancer 2012-06-05

...Pgp. We investigated the role of ezrin in a human multidrug-resistant osteosarcoma cell line overexpressing Pgp and comp...

Modulation of P-glycoprotein expression by cytochrome P450 3A inducers in male …

Salphati(L),Benet(L Z) Biochem Pharmacol 1998-04-09

...Pgp) and cytochrome P450 3A (CYP3A) substrates and modulators has been reported. To test the hypothesis that CYP3A and P...

Overexpression of the class II P-glycoprotein gene in primary rat hepatocyte cu…

Lee(C H),Bradley(G),Ling(V) Cell Growth Differ 1995-08-03

...Pgp as a function of the time in culture. This isoform of Pgp, which is expressed at a very low level in normal liver, h...

The farnesyl protein transferase inhibitor SCH66336 is a potent inhibitor of MD…

Wang(E),Casciano(C N),Clement(R P),Johnson(W… Cancer Res 2001-12-04

...Pgp. In a test system consisting of a NIH-G185 cell line presenting an overexpressed amount of the human transporter Pgp...

The potential inhibitory effect of antiparasitic drugs and natural products on …

Hayeshi(Rose),Masimirembwa(Collen),Mukangany… Eur J Pharm Sci 2006-10-19

...Pgp substrate. The rest of the compounds inhibiting Pgp showed no evidence of being Pgp substrates. In conclusion, we ha...

Biochemical and pharmacological properties of an allosteric modulator site of t…

Maki(Nazli),Dey(Saibal) Biochem Pharmacol 2006-08-22

...Pgp-mediated drug transport by an allosteric mechanism. Unlike most other Pgp modulators, the cis isomer of flupentixol ...

Evaluation of Pgp (MDR1) immunohistochemistry in canine lymphoma - prognostic a…

Vajdovich(P),Koltai(Z),Dékay(V),Kungl(K),Har… Acta Vet Hung 2018-00-00

...Pgp analyses (with anti-Pgp, monoclonal mouse C494 clone) were performed. Pgp positivity rate and intensity were determi...

Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation.

Padowski(Jeannie M),Pollack(Gary M) Methods Mol Biol 2010-01-05

...Pgp modulation for a given Pgp substrate in order to predict the degree to which Pgp modulation may affect that substrat...

Herbal modulation of P-glycoprotein.

Zhou(Shufeng),Lim(Lee Yong),Chowbay(Balram) Drug Metab Rev 2004-11-16

...Pgp protein or intact Pgp-expressing cells, and proper probe substrates and inhibitors. Curcumin, ginsenosides, piperine...

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