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Protein S controls hypoxic/ischemic blood-brain barrier disruption through th...

Zhu(Donghui),Wang(Yaoming),Singh(Itender),... Blood 2010-07-19

...Tyro3 phosphorylation, and Tyro3-, Axl- and Mer-deficient mouse brain endothelial cells, we show that Tyro3 mediates PS ...

TNF-alpha, IL-6, and IL-1 expression is inhibited by GAS6 in monocytes/macrop...

Alciato(Federica),Sainaghi(Pier Paolo),Sol... J Leukoc Biol 2010-05-20

...Tyro3) is expressed on differentiated U937 cells, and its activation is responsible for the reduction of cytokine expres...

Gas6 is complexed to the soluble tyrosine kinase receptor Axl in human blood.

Ekman(C),Stenhoff(J),Dahlbäck(B) J Thromb Haemost 2010-07-08

...Tyro3, Axl and Mer. It has been suggested that Gas6 and the TAM receptors are important for primary platelet functions, ...

A genomic screen identifies TYRO3 as a MITF regulator in melanoma.

Zhu(Shoutian),Wurdak(Heiko),Wang(Yan),Galk... Proc Natl Acad Sci U S A 2010-01-15

...TYRO3 as an upstream regulator of MITF expression by a genome-wide gain-of-function cDNA screen and show that TYRO3 indu...

TAM receptor signalling and demyelination.

Binder(Michele D),Kilpatrick(Trevor J) Neurosignals 2010-01-11

...Tyro3, Axl and Mer) of receptor protein tyrosine kinases play pivotal roles in a number of major cellular processes: cel...

Malignant cells fuel tumor growth by educating infiltrating leukocytes to pro...

Loges(Sonja),Schmidt(Thomas),Tjwa(Marc),va... Blood 2010-04-13

...Tyro3, Axl, and Mer (TAM) family of receptor tyrosine kinases (TAMRs), are well recognized. In contrast, little is known...

Association study between polymorphims in GAS6-TAM genes and carotid atherosc...

Hurtado(Begoña),Abasolo(Nerea),Muñoz(Xavie... Thromb Haemost 2010-12-08

...TYRO3, AXL and MERTK (TAM) may have a relevant role in atherogenesis. Furthermore, our previous studies indicated an ass...

Protein S protects neurons from excitotoxic injury by activating the TAM rece...

Zhong(Zhihui),Wang(Yaoming),Guo(Huang),Sag... J Neurosci 2010-12-23

...Tyro3-, Axl-, and Mer-deficient neurons, we showed that PS protected neurons lacking Axl and Mer, but not Tyro3, suggest...

TAM receptors and the clearance of apoptotic cells.

Lemke(Greg),Burstyn-Cohen(Tal) Ann N Y Acad Sci 2010-11-08

...Tyro3, Axl, and Mer (TAM) receptor tyrosine kinases and their ligands Gas6 and Protein S are required for the optimal ph...

Sertoli cell-initiated testicular innate immune response through toll-like re...

Sun(Bing),Qi(Nan),Shang(Tao),Wu(Hui),Deng(... Endocrinology 2010-06-30

...Tyro3 subfamily of receptor tyrosine kinases, Tyro3, Axl, and Mer (TAM), negatively regulate TLR3 signaling in Sertoli c...

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