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TP53 BRCA1 CRISPR single-cell cancer

Blanke(C D),Demetri(G D),Von Mehren(M),Hei... J Clin Oncol 0000-00-00

...PDGFRA mutational analyses were obtained in 87% of patients, and the mutational status was highly significant in predict...

Heinrich(M C),Maki(R G),Corless(C L),Anton... J Clin Oncol 0000-00-00

...PDGFRA (4 pts, CB 25%), no KIT or PDGFRA mutation (wild-type [WT]; 9 pts, CB 56%). Notably, the PR rate for GISTS with p...

Heinrich(M C),Shoemaker(J S),Corless(C L),... J Clin Oncol 0000-00-00

7 Background: Most GISTs express constitutively activated mutant isoforms of the KIT or PDGFRA tyrosine kinases that are...

Maki(R G),Fletcher(J A),Heinrich(M C),Morg... J Clin Oncol 0000-00-00

...PDGFRA) tyrosine kinases. SU11248 is an oral multi-targeted tyrosine kinase inhibitor with both anti-angiogenic and dire...

Blackstein(M E),Rankin(C),Fletcher(C),Hein... J Clin Oncol 0000-00-00

...PDGFRA.,Pathology has been reviewed on 414 pts: 377 (91%) had KIT+ GIST, 14 (3%) KIT- GIST, and 16 (4%) leiomyosarcoma/o...

Martin-Broto(J),Martinez-Marín(V),Serrano(... Clin Transl Oncol 0000-00-00

...PDGFRA; less commonly, GISTs have also been reported to display mutations elsewhere, including BRAF and NF1 and SDH-comp...

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