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Renal aquaporins and water balance disorders.

Kortenoeven(Marleen L A),Fenton(Robert A) Biochim Biophys Acta 2014-05-09

...AQP2, AQP3, AQP4 and AQP7. AQP2 in particular is regulated by vasopressin.,This review summarizes our current knowledge ...

GATA2 regulates body water homeostasis through maintaining aquaporin 2 expres...

Yu(Lei),Moriguchi(Takashi),Souma(Tomokazu)... Mol Cell Biol 2014-07-10

...Aqp2 promoter region. A luciferase reporter assay using an Aqp2 promoter-reporter showed that GATA2 trans activates Aqp2...

Aquaporins: important but elusive drug targets.

Verkman(Alan S),Anderson(Marc O),Papadopou... Nat Rev Drug Discov 2014-05-19

...AQP2), and autoantibodies against AQP4 cause the autoimmune demyelinating disease neuromyelitis optica. Although some po...

Use of LC-MS/MS and Bayes' theorem to identify protein kinases that phosphory...

Bradford(Davis),Raghuram(Viswanathan),Wils... Am J Physiol Cell Physiol 2014-09-05

...AQP2) at Ser256. The protein kinase that phosphorylates this site is not known. We use Bayes' theorem to rank all 521 ra...

The role of the renal ammonia transporter Rhcg in metabolic responses to diet...

Bounoure(Lisa),Ruffoni(Davide),Müller(Ralp... J Am Soc Nephrol 2014-11-21

...AQP2, with less phosphorylation of AQP2 at serine 256. The high protein acid load affected bone turnover, as indicated b...

The association of transporter genes polymorphisms and lung cancer chemothera...

Wang(Ying),Yin(Ji-Ye),Li(Xiang-Ping),Chen(... PLoS One 2014-12-19

...AQP2 rs7314734 showed significant relation to chemotherapy response. In conclusion, the genetic polymorphisms in OCT2, A...

Elevated cAMP increases aquaporin-3 plasma membrane diffusion.

Marlar(Saw),Arnspang(Eva C),Koffman(Jennif... Am J Physiol Cell Physiol 2014-05-13

...AQP2) are inserted into the apical membrane instantly increasing water reabsorption and urine concentration. The reabsor...

Excretion of urinary exosomal AQP2 in rats is regulated by vasopressin and ur...

Higashijima(Yoshiki),Sonoda(Hiroko),Takaha... Am J Physiol Renal Physiol 2014-01-16

...AQP2 are largely unknown. In this study, we examined the mechanisms of urinary exosomal AQP2 excretion in vivo, using di...

Unraveling aquaporin interaction partners.

Sjöhamn(Jennie),Hedfalk(Kristina) Biochim Biophys Acta 2014-05-09

...AQP2, AQP4 and AQP5.,The vast majority of interactions involve the aquaporin C-terminus and the characteristics of the i...

Generation of a tenascin-C-CreER2 knockin mouse line for conditional DNA reco...

He(Wenjuan),Xie(Qionghong),Wang(Yingying),... PLoS One 2014-08-12

...AQP2 or AQP1, suggesting selective expression in RMICs. After recombination (tenascin-C-CreER2(+/-)/ROSA26-lacZ(+/-) mic...

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