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Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 6 Protects Cartilag...

Chen(Y),Li(Y),Chen(D),Yang(J),Kang(H),Wang(F) Antioxid Redox Signal 2026-02-00

...COL2A1), and matrix metalloproteinase (MMP)13. LGR6 KO exacerbated OA severity, cartilage degradation, and inflammatory ...

Bioactive-Rich Piper sarmentosum Aqueous Extract Mitigates Osteoarthritic Pat...

Lee(YT),Mohd Yunus(MH),Abdul Rani(R),Ng(CY... Biomedicines 2026-01-08

...COL2A1, ACP, SOX9) and sGAG production, while concurrently suppressing COX2 expression and NO synthesis. Additionally, P...

Socceromics: A Systematic Review of Omics Technologies to Optimize Performanc...

Owen(A),Ceylan(Hİ),Zmijewski(P),Biz(C),Sci... Int J Mol Sci 2026-01-12

...COL2A1, COL5A1, COL12A1, COL22A1, ELN, EMILIN1, TNC, MMP3, GEFT, LIF, HGF) were implicated in ligament, tendon, and musc...

RICTOR-mediated GPX4 downregulation regulates chondrocyte ferroptosis in oste...

Xu(J),Zheng(Z),Xin(F),Zhang(X),Hou(L),Zhon... Int Immunopharmacol 2026-03-15

...Col2a1 and promoted down-regulation of MMP13. Moreover, the RICTOR inhibitor JR-AB2 ameliorated cartilage degradation in...

Self-assembled silk fibroin hydrogels with precisely engineered viscoelastici...

Yao(D),Xia(Z),Zhou(J),Hua(N),Wang(L),Xu(M) Int J Biol Macromol 2026-02-00

...COL2A1, and enhanced the secretion of glycosaminoglycans (GAGs). The newly formed tissue exhibited a smooth surface and ...

Bifidobacterium longum CBi0703 lysate modulates oxidative stress induced apop...

Mas-Capdevila(A),Carrera-Marcolin(L),Balag... Sci Rep 2026-01-29

...COL2A1, SOX9, AGC1, TIMP1) markers compared with the OA-induced vehicle. The combination with vitamin C upregulated SOX9...

Semaphorin 7A Regulates the Balance Between Cartilaginous and Fibrous Tissues...

Hatada(R),Abe(K),Yamashita(A),Horike(N),Ob... Cartilage 2026-01-31

...Col2a1 and Col9a1 expression, suggesting that integrin β1 mediates Sema7A function. Sema7A knockout mice showed signific...

Effect of HIF-1α inhibitor LW6 on chondrogenic properties of mesenchymal stro...

Lebedis(I),Pachaleva(J),Bernotiene(E),Biro... J Biol Eng 2026-01-09

...COL2A1, ACAN) in both cell types. LW6 further reduced metabolic activity and calcium levels, degraded HIF-1α and downreg...

Salmon Nasal Cartilage Proteoglycan Ameliorate Joint Pain and Cartilage Degra...

Yu(M),Jo(SE),Son(YB),Kim(YJ),Seo(Y),Han(SB... Nutrients 2026-01-05

...COL2A1), and aggrecan (ACAN) typically observed in the disease's later stages. While SPG demonstrated a limited impact o...

Genetics of GH Deficiency: Insights From a Cohort of 203 Patients.

Ribeiro(AC),Coutinho(E),Syed(N),Bastos(M),... J Clin Endocrinol Metab 2026-01-21

...COL2A1 (0.5%), GHRHR (0.5%), PTPN11 (0.5%), and SOX3 (0.5%) genes. One patient (0.5%) had a digenic mutation in the BMP4...

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