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Li(Qingjie),Winston(John H),Sarna(Sushil K... Am J Physiol Regul Integr C... 2016-06-09

...PDK1), pAKT(Ser473), and phosphorylated 4E-binding protein (p4E-BP1)(Thr70), suggesting AKT activation and enhanced NGF ...

Yu(Zhi-Liang),Wang(Jie-Ning),Wu(Xiao-Hua),... J Cardiovasc Pharmacol Ther 2016-07-13

...PDK1/AKT pathway by cellular, molecular, and biochemical approaches. Our results revealed that the abundance of PDK1 in ...

Wada(Makoto),Horinaka(Mano),Yasuda(Shusuke... J Dermatol Sci 2016-03-21

...PDK1 to examine the role of PDK1 on the growth of angiosarcoma cells.,The PI3K inhibitor and mTOR inhibitor inhibited th...

Scortegagna(Marzia),Lau(Eric),Zhang(Tongwu... Cancer Res 2016-01-23

...PDK1, as elucidated recently in studies of Braf::Pten mutant melanomas. Here, we report that PDK1 contributes functional...

Lu(Shaoyong),Deng(Rong),Jiang(Haiming),Son... Structure 2016-06-27

...PDK1 and PP2A phosphatase recruitment. We further probed the function of residues around pT308 at the atomic level, and ...

Huang(Feng),Hu(Xiaoxiao),Fang(Chunni),Liu(... Histochem Cell Biol 2016-08-17

...PDK1 expression reveal spatial and temporal patterns of FGF signaling during morphogenesis and organogenesis of human to...

Lucero-Acuña(Armando),Guzmán(Roberto) Int J Pharm 2016-09-06

...PDK1 loaded nanoparticles over BxPC-3 pancreatic cancer cells in vitro. These studies show that the encapsulated inhibit...

Kim(Nam-Gyun),Gumbiner(Barry M) J Cell Biol 2016-04-26

...PDK1 activity blocked YAP nuclear accumulation stimulated by adhesion to fibronectin. This negative regulation of the Hi...

Tsuchiya(Ayako),Kanno(Takeshi),Shimizu(Tad... J Pharmacol Sci 2016-05-31

...PDK1)/Akt axis, that mimics insulin signaling. Moreover, diDCP-LA-PE-induced GLUT4 translocation was suppressed by inhib...

Gagliardi(Paolo Armando),di Blasio(Laura),... Biochim Biophys Acta 2016-02-23

...PDK1 in the regulation of cell migration. PDK1 is a transducer of PI3K signaling and activates multiple downstream effec...