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A novel tumor suppressor role of myosin light chain kinase splice variants thro…

Huang(YJ),Lee(TC),Pai(YC),Lin(BR),Turner(JR)… Carcinogenesis 2021-00-16

...TEAD4 (a transcriptional enhancer factor family member in the Hippo pathway) to CD44 promoter, which was confirmed by lu...

Expression of microRNA let-7 in cleavage embryos modulates cell fate determinat…

Liu(W),Chen(J),Yang(C),Lee(KF),Lee(YL),Chiu(… Biol Reprod 2022-00-10

...Tead4 and let-7 forced expression downregulated the expression of Tead4 in mouse blastocysts. Co-injection of Tead4 mRNA...

Metformin targets a YAP1-TEAD4 complex via AMPKα to regulate CCNE1/2 in bladder…

Wu(Y),Zheng(Q),Li(Y),Wang(G),Gao(S),Zhang(X)… J Exp Clin Cancer Res 2019-08-27

...TEAD4 was highly expressed and positively associated with the expressions of CCNE1 and CCNE2 in BLCA and only TEAD4 was ...

Integrative machine learning identifies a TEAD4-driven endothelial program shap…

Zhang(P),Song(H),Lin(S),Zhu(Y) J Transl Med 2026-02-09

...TEAD4 emerged as the dominant downstream transcription factor, driving APLN, ANGPT2, and VEGFA expression. TEAD4 inhibit...

A framework for TRIM21-mediated protein depletion in early mouse embryos: recap…

Israel(S),Casser(E),Drexler(HCA),Fuellen(G),… BMC Genomics 2019-10-21

...Tead4) gene. TEAD4 depletion starting at the 1-cell stage lasts for 3 days prior to a return of gene and protein express...

Integrated analysis identifies conserved transcription factors TCF12, E2F1, and…

Cheng(J),Cai(R),Lu(W),Zhang(Z),Liang(H),Chen… Genes Genomics 2025-11-26

...TEAD4 were down-regulated in human OA subchondral bone and mouse DMM model. This study highlights TCF12, E2F1, and TEAD4...

Intrinsic and acquired drug resistance to LSD1 inhibitors in small cell lung ca…

Yan(W),Chung(CY),Xie(T),Ozeck(M),Nichols(TC)… Mol Oncol 2022-00-00

...TEAD4-driven mesenchymal-like state. Our data suggest that only a segment of SCLC patients, with a defined neuroendocrin...

O-GlcNAcylation controls pro-fibrotic transcriptional regulatory signaling in m…

Very(N),Boulet(C),Gheeraert(C),Berthier(A),J… Cell Death Dis 2024-00-03

...TEAD4) together with the Yes-associated protein 1 (YAP1) co-activator. Indeed, inhibition of protein O-GlcNAcylation imp...

KAT6A/YAP/TEAD4 pathway modulates osteoclastogenesis by regulating the RANKL/OP…

Tan(K),Wang(J),Su(X),Zheng(Y),Li(W) Prog Orthod 2024-08-12

...TEAD4 interaction inhibitor, partly attenuated the elevation of the RANKL/OPG ratio induced by mechanical force. Our stu...

Identification of New Transcription Factors that Can Promote Pluripotent Reprog…

Huang(P),Zhu(J),Liu(Y),Liu(G),Zhang(R),Li(D)… Stem Cell Rev Rep 2021-12-00

...TEAD4 and ZIC3 as potential factors involved in urine cell reprogramming. Transfection of TEAD2, TEAD4 and ZIC3 (in the ...

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