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Myc-Driven Glycolysis Is a Therapeutic Target in Glioblastoma.

Tateishi(Kensuke),Iafrate(A John),Ho(Quan)... Clin Cancer Res 0000-00-00

...MYCN amplification. The in vivo efficacy of glycolyic inhibition was tested using NAMPT inhibitors in MYCN-amplified pat...

A Rapid and Sensitive Next-Generation Sequencing Method to Detect RB1 Mutatio...

Li(Wenhui L),Buckley(Jonathan),Sanchez-Lar... J Mol Diagn 0000-00-00

...MYCN amplification. Timely identification of a germline RB1 mutation in blood samples or either somatic RB1 mutation or ...

Identification of cooperative genes for E2A-PBX1 to develop acute lymphoblast...

Sera(Yasuyuki),Yamasaki(Norimasa),Oda(Hide... Cancer Sci 0000-00-00

...Mycn, and Pim1 genes. In addition, it is of note that viral integration and overexpression of the Zfp521 gene was detect...

MYCN Transforms Prostate Epithelium to Neuroendocrine Prostate Cancer.

Cancer Discov 0000-00-00

...MYCN in normal basal prostate cells drives formation of metastatic NEPC.

Comparative analysis of copy number variations in ulcerative colitis associat...

Shivakumar(B M),Chakrabarty(Sanjiban),Rott... BMC Cancer 0000-00-00

...MYCN, CCND1, CCND2, EGFR and FNDC3A was successful in detecting neoplasia with an overall accuracy of 54% in S-CRN compa...

Childhood Neuroblastoma: Incidence and Survival in Argentina. Report from the...

Moreno(Florencia),Lopez Marti(Jessica),Pal... Pediatr Blood Cancer 0000-00-00

...MYCN 15%. Residents in provinces with a higher EHDI had a better 5-year survival (57% vs. 41% for lower EHDI) and higher...

Somatic genomic alterations in retinoblastoma beyond RB1 are rare and limited...

Kooi(Irsan E),Mol(Berber M),Massink(Maarte... Sci Rep 0000-00-00

...MYCN amplification, while additional alterations may be required for tumor development. However, the view on single nucl...

MYCN-targeting vaccines and immunotherapeutics.

Schramm(Alexander),Lode(Holger) Hum Vaccin Immunother 0000-00-00

...MYCN. However, MYCN is a transcription factors that was considered a poor drug target, until recent approaches suggested...

Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is me...

He(Shuning),Mansour(Marc R),Zimmerman(Mark... Elife 0000-00-00

...MYCN-induced neuroblastomas that arise in these precursors, and that the GTPase-activating protein (GAP)-related domain ...

The Bromodomain BET Inhibitor JQ1 Suppresses Tumor Angiogenesis in Models of ...

Bid(Hemant K),Phelps(Doris A),Xaio(Linlin)... Mol Cancer Ther 0000-00-00

...MYCN. In vivo, xenografts showed significant inhibition of growth during the period of treatment, and rapid regrowth aft...

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